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INDO wt Allele
Known as:
IDO
, IDO1
, Indoleamine-Pyrrole 2,3 Dioxygenase wt Allele
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Human INDO wild-type allele is located within 8p12-p11 and is approximately 15 kb in length. This allele, which encodes indoleamine 2,3-dioxygenase…
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National Institutes of Health
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Related topics
Related topics
5 relations
IDO1 gene
Oxidation-Reduction
Tryptophan Metabolism Pathway
indole 2,3-dioxygenase activity
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2015
2015
IDO1 suppresses inhibitor development in hemophilia A treated with factor VIII.
D. Matino
,
M. Gargaro
,
+29 authors
F. Fallarino
Journal of Clinical Investigation
2015
Corpus ID: 20166179
The development of inhibitory antibodies to factor VIII (FVIII) is a major obstacle in using this clotting factor to treat…
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Highly Cited
2014
Highly Cited
2014
Preliminary results from a phase 1/2 study of INCB024360 combined with ipilimumab (ipi) in patients (pts) with melanoma.
G. Gibney
,
O. Hamid
,
+12 authors
Jeffrey S. Weber
2014
Corpus ID: 77469508
3010 Background: Indoleamine 2,3-dioxygenase 1 (IDO1) is a tryptophan-catabolizing enzyme that is overexpressed in cancers and…
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2013
2013
Resveratrol suppresses tumor progression via the regulation of indoleamine 2,3-dioxygenase.
K. Noh
,
Seungbum Chae
,
S. Chun
,
I. Jung
,
H. Kang
,
Yeong-Min Park
Biochemical and Biophysical Research…
2013
Corpus ID: 20847362
2011
2011
Effects of PEG-interferon alpha plus ribavirin on tryptophan metabolism in patients with chronic hepatitis C.
S. Comai
,
L. Cavalletto
,
+4 authors
A. Bertazzo
Pharmacological Research
2011
Corpus ID: 24288862
Review
2011
Review
2011
Regulation of expression and function of IDO in human dendritic cells.
A. Heitger
Current Medicinal Chemistry
2011
Corpus ID: 24523867
In the human immune system, IDO expression and activity (IDO competence), are preferentially found in the antigenpresenting cell…
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Highly Cited
2011
Highly Cited
2011
Enhanced tryptophan degradation in patients with ovarian carcinoma correlates with several serum soluble immune activation markers.
B. Sperner-Unterweger
,
G. Neurauter
,
+4 authors
D. Fuchs
Immunobiology
2011
Corpus ID: 24120784
2009
2009
Human Activated T Lymphocytes Modulate IDO Expression in Tumors through Th1/Th2 Balance1
J. Godin-Ethier
,
S. Pelletier
,
+9 authors
R. Lapointe
Journal of Immunology
2009
Corpus ID: 9214688
Previous cancer vaccination approaches have shown some efficiency in generating measurable immune responses, but they have rarely…
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2007
2007
Suppression of islet allogeneic immune response by indoleamine 2,3 dioxygenase‐expressing fibroblasts
R. Jalili
,
G. Rayat
,
R. Rajotte
,
A. Ghahary
Journal of Cellular Physiology
2007
Corpus ID: 35161403
Success of transplantation of pancreatic islets which is a promising way for restoring efficient insulin regulation in type 1…
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Review
2005
Review
2005
Marrying immunotherapy with chemotherapy: why say IDO?
A. Muller
,
G. Prendergast
Cancer Research
2005
Corpus ID: 6925725
Activation of the tryptophan catabolizing enzyme indoleamine 2,3-dioxygenase (IDO) in cancer cells facilitates immune escape. A…
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2002
2002
HeLa cells cocultured with peripheral blood lymphocytes acquire an immuno‐inhibitory phenotype through up‐regulation of indoleamine 2,3‐dioxygenase activity
G. Logan
,
C. Smyth
,
+4 authors
I. Alexander
Immunology
2002
Corpus ID: 20791545
The mechanisms by which tumour cells escape recognition by the immune system or subvert antitumour effector responses remain…
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