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ILK gene

Known as: ILK, p59, Integrin-Linked Kinase Gene 
This gene plays a role in the regulation of signal transduction and cell adhesion. It is also involved in cell organization.
National Institutes of Health

Papers overview

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Highly Cited
2011
Highly Cited
2011
Dopaminergic (DA) neuron degeneration is a feature of brain aging but is markedly increased in patients with Parkinson’s disease… Expand
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Highly Cited
2008
Highly Cited
2008
The human kidneys filter 180 l of blood every day via about 2.5 million glomeruli. The three layers of the glomerular filtration… Expand
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Highly Cited
2006
Highly Cited
2006
A requirement for integrin-mediated adhesion in cardiac physiology is revealed through targeted deletion of integrin-associated… Expand
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Highly Cited
2003
Highly Cited
2003
Integrin-mediated cell-matrix interactions are essential for development, tissue homeostasis, and repair. Upon ligand binding… Expand
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Highly Cited
2003
Highly Cited
2003
Activation of integrin receptors in neurons can promote cell survival and synaptic plasticity, but the underlying signal… Expand
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Highly Cited
2001
Highly Cited
2001
Loss of functional adenomatous polyposis coli (APC) protein results in the stabilization of cytosolic β-catenin and activation of… Expand
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Highly Cited
2001
Highly Cited
2001
The integrin linked kinase (ILK) is a cytoplasmic effector of integrin receptors, involved in the regulation of integrin binding… Expand
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Highly Cited
2001
Highly Cited
2001
Abstract The seminiferous epithelium contains unique actin related cell-cell junctions, termed ectoplasmic specializations (ESs… Expand
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Highly Cited
2000
Highly Cited
2000
Disruption of integrin-extracellular matrix interactions in normal epithelial cells induces apoptosis, a process termed anoikis… Expand
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Highly Cited
2000
Highly Cited
2000
Overexpression of Integrin Linked Kinase (ILK) in intestinal and mammary epithelial cells results in a highly invasive phenotype… Expand
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