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ILK gene

Known as: ILK, p59, Integrin-Linked Kinase Gene 
This gene plays a role in the regulation of signal transduction and cell adhesion. It is also involved in cell organization.
National Institutes of Health

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ILK wt Allele
Serine/Threonine PhosphorylationSignal Transductionintegrin-linked kinase

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2019
Highly Cited
2019
Binding mechanism of caffeic acid and simvastatin to the integrin linked kinase for therapeutic implications: a comparative docking and MD simulation studies
Abstract Integrin linked kinase (ILK) is a Ser/Thr kinase, which regulates various integrin mediated signaling pathways, and is… 
Review
2015
Review
2015
Transcriptional Activation of Inflammatory Genes: Mechanistic Insight into Selectivity and Diversity
Acute inflammation, an integral part of host defence and immunity, is a highly conserved cellular response to pathogens and other… 
Highly Cited
2014
Highly Cited
2014
Differences in binding to the ILK complex determines kindlin isoform adhesion localization and integrin activation
ABSTRACT Kindlins are essential FERM-domain-containing focal adhesion (FA) proteins required for proper integrin activation and… 
Highly Cited
2014
Highly Cited
2014
β1-Integrin and Integrin Linked Kinase Regulate Astrocytic Differentiation of Neural Stem Cells
Astrogliosis with glial scar formation after damage to the nervous system is a major impediment to axonal regeneration and… 
Highly Cited
2011
Highly Cited
2011
The mechanism of contribution of integrin linked kinase (ILK) to epithelial-mesenchymal transition (EMT).
Review
2009
Review
2009
A comparative analysis of the cell biology of senescence and aging
Various intracellular organelles, such as lysosomes, mitochondria, nuclei, and cytoskeletons, change during replicative… 
Highly Cited
2005
Highly Cited
2005
Formation and phosphorylation of the PINCH-1-integrin linked kinase-alpha-parvin complex are important for regulation of renal glomerular podocyte adhesion, architecture, and survival.
Alterations in the cellular architecture, adhesion, and/or loss of glomerular podocytes are causal factors in the development of… 
2002
2002
Integrin Adhesion: When Is a Kinase a Kinase?
Highly Cited
2001
Highly Cited
2001
Rat Seminiferous Epithelium Contains a Unique Junction (Ectoplasmic Specialization) with Signaling Properties Both of Cell/Cell and Cell/Matrix Junctions
Abstract The seminiferous epithelium contains unique actin related cell-cell junctions, termed ectoplasmic specializations (ESs… 
Highly Cited
1998
Highly Cited
1998
ILK (β1-integrin-linked protein kinase): a novel immunohistochemical marker for Ewing’s sarcoma and primitive neuroectodermal tumour
Abstract ILK (β1-integrin-linked protein kinase) is a recently identified 59-kDa serine/threonine protein kinase that interacts… 
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