ILK gene

Known as: ILK, p59, Integrin-Linked Kinase Gene 
This gene plays a role in the regulation of signal transduction and cell adhesion. It is also involved in cell organization.
National Institutes of Health

Papers overview

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Review
2016
Review
2016
Cardiac fibrosis is one of the major components of the healing mechanism following any injury of the heart and as such may… (More)
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2010
2010
In a previous study it was found that the therapeutic effects of QLT0267, a small molecule inhibitor of integrin-linked kinase… (More)
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Highly Cited
2006
Highly Cited
2006
A requirement for integrin-mediated adhesion in cardiac physiology is revealed through targeted deletion of integrin-associated… (More)
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2004
2004
ILKAP is a protein phosphatase 2C that selectively associates with integrin linked kinase, ILK, to modulate cell adhesion and… (More)
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Highly Cited
2003
Highly Cited
2003
Integrin-mediated cell-matrix interactions are essential for development, tissue homeostasis, and repair. Upon ligand binding… (More)
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2003
2003
Activation of integrin receptors in neurons can promote cell survival and synaptic plasticity, but the underlying signal… (More)
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Highly Cited
2001
Highly Cited
2001
Loss of functional adenomatous polyposis coli (APC) protein results in the stabilization of cytosolic β-catenin and activation of… (More)
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Highly Cited
2001
Highly Cited
2001
The integrin linked kinase (ILK) is a cytoplasmic effector of integrin receptors, involved in the regulation of integrin binding… (More)
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Highly Cited
2000
Highly Cited
2000
Disruption of integrin-extracellular matrix interactions in normal epithelial cells induces apoptosis, a process termed anoikis… (More)
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Highly Cited
2000
Highly Cited
2000
Overexpression of Integrin Linked Kinase (ILK) in intestinal and mammary epithelial cells results in a highly invasive phenotype… (More)
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