integrin-linked kinase

Known as: ILK, p59 ILK, p59(ILK) 
Transduction of extracellular matrix signals through integrins influences intracellular and extracellular functions, and appears to require… (More)
National Institutes of Health

Papers overview

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Review
2008
Review
2008
Integrin-linked kinase (ILK) is a multifunctional intracellular effector of cell-matrix interactions and regulates many cellular… (More)
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Review
2006
Review
2006
The ternary complex of integrin-linked kinase (ILK), PINCH and parvin functions as a signalling platform for integrins by… (More)
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Review
2005
Review
2005
Cancer development requires the acquisition of several capabilities that include increased replicative potential, anchorage and… (More)
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Highly Cited
2004
Highly Cited
2004
We show that integrin-linked kinase (ILK) stimulates the expression of VEGF by stimulating HIF-1alpha protein expression in a PKB… (More)
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Highly Cited
2003
Highly Cited
2003
Under pathologic conditions, renal tubular epithelial cells can undergo epithelial to mesenchymal transition (EMT), a phenotypic… (More)
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Highly Cited
2003
Highly Cited
2003
Integrin-mediated cell-matrix interactions are essential for development, tissue homeostasis, and repair. Upon ligand binding… (More)
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Highly Cited
2001
Highly Cited
2001
Protein kinase B (PKB/Akt) is a regulator of cell survival and apoptosis. To become fully activated, PKB/Akt requires… (More)
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Highly Cited
2000
Highly Cited
2000
Disruption of integrin-extracellular matrix interactions in normal epithelial cells induces apoptosis, a process termed anoikis… (More)
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Highly Cited
1998
Highly Cited
1998
Integrin-linked kinase (ILK) is an ankyrin-repeat containing serine-threonine protein kinase capable of interacting with the… (More)
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Highly Cited
1996
Highly Cited
1996
THE interaction of cells with the extracellular matrix regulates cell shape, motility, growth, survival, differentiation and gene… (More)
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