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IL3 protein, human

Known as: Mast-Cell Growth Factor, MULTI-CSF, Interleukin 3 
One of a group of related proteins made by leukocytes (white blood cells) and other cells in the body. IL-3 is made mainly by a type of T lymphocyte… 
National Institutes of Health

Related topics

Related topics

26 relations
ApoptosisBone MarrowCell Differentiation processCell Proliferation

Broader (1)

Interleukin-3

Narrower (1)

Recombinant Interleukin-3

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2013
2013
IL3 Induces Osteoclastogenesis In Vivo and Is Modulated By Bone Marrow Monocyte / Macrophage Derived Activin A
Multiple myeloma (MM) bone disease is characterized by bone destruction with suppressed bone formation resulting in enhanced… 
2005
2005
β1 integrin and IL-3R coordinately regulate STAT5 activation and anchorage-dependent proliferation
We previously demonstrated that integrin-dependent adhesion activates STAT5A, a well known target of IL-3–mediated signaling… 
1997
1997
Redox regulation of apoptosis in interleukin‐3‐dependent haemopoietic cells: absence of alteration in both mitochondrial membrane potential (Δψm) and free radical production during apoptosis induced…
Apoptosis in haemopoietic cells has been linked to the production of free radicals and reduction in mitochondrial transmembrane… 
Highly Cited
1995
Highly Cited
1995
Effects of T-helper 2-type cytokines, interleukin-3 (IL-3), IL-4, IL-5, and IL-6 on the survival of cultured human mast cells.
Although stem cell factor (SCF) has been identified as a critical cytokine for the development of human mast cells from their… 
1994
1994
Production of IL2 and IL3 in syngeneic mixed lymphocyte reactions of BALB/c mice are elevated during a period of moderate dietary protein deficiency.
The mixed lymphocyte reaction (MLR) is a model of T cell responsiveness to antigenic peptides complexed with major… 
Highly Cited
1993
Highly Cited
1993
Altered metabolism of mast-cell growth factor (c-kit ligand) in cutaneous mastocytosis.
BACKGROUND AND METHODS The lesions of cutaneous mastocytosis are characterized by dermal infiltrates of mast cells and may appear… 
1991
1991
Increased response of erythroid progenitors to interleukin‐3 in sickle cell anemia: CFU‐E‐like behavior of circulating erythroid progenitors in liquid culture
Erythroid progenitors circulating in peripheral blood and their response to erythropoietin (EPO), interleukin‐3 (IL3), and… 
Highly Cited
1987
Highly Cited
1987
Human keratinocytes and epidermoid carcinoma cell lines produce a cytokine with interleukin 3-like activity.
Keratinocytes are capable of releasing distinct immunomodulating cytokines such as epidermal cell-derived thymocyte activating… 
Highly Cited
1986
Highly Cited
1986
Characterization of a murine lymphokine distinct from interleukin 2 and interleukin 3 (IL-3) possessing a T-cell growth factor activity and a mast-cell growth factor activity that synergizes with IL…
Murine mast-cell and T-cell growth factor activities, distinct from interleukins 3 and 2 (IL-3 and IL-2), have been identified… 
1985
1985
Ultrastructure of human basophils developing in vitro. Evidence for the acquisition of peroxidase by basophils and for different effects of human and murine growth factors on human basophil and…
We examined the ultrastructure of human fetal cord blood mononuclear cells cultured in medium supplemented with supernatants of… 
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