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Interleukin-3

Known as: Interleukin-3 [Chemical/Ingredient], Interleukin 3, Hematopoietin 2 
A multilineage cell growth factor secreted by LYMPHOCYTES; EPITHELIAL CELLS; and ASTROCYTES which stimulates clonal proliferation and differentiation… 
National Institutes of Health

Related topics

Related topics

27 relations
Colony-Stimulating FactorsGranulocyte-Macrophage Colony-Stimulating FactorIn BloodInterleukin 3 Measurement

Broader (2)

Hematopoietic Cell Growth FactorsLymphokines

Narrower (7)

IL3 protein, humanPIXY321 fusion protein, recombinantRecombinant Interleukin-3daniplestim

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2007
Highly Cited
2007
Combined analysis of intracellular signalling and immunophenotype of human peripheral blood basophils by flow cytometry: a proof of concept
Background The signal transduction pathways and control mechanisms involved in IgE‐mediated basophil activation remain… 
Highly Cited
1996
Highly Cited
1996
Nonreleasing basophils convert to releasing basophils by culturing with IL-3.
Highly Cited
1995
Highly Cited
1995
TRAUMA-HEMORRHAGE CAUSES PROLONGED DEPRESSION IN CELLULAR IMMUNITY
ABSTRACT A number of clinical studies have shown that multiple and severe trauma causes immunosuppression and increases the… 
Highly Cited
1994
Highly Cited
1994
Interleukin (IL)-3 and granulocyte/macrophage colony-stimulating factor, but not IL-4, induce tyrosine phosphorylation, activation, and association of SHPTP2 with Grb2 and phosphatidylinositol 3…
Binding of interleukin (IL)-3 and granulocyte/macrophage colony-stimulating factor (GM-CSF) to their high affinity cell surface… 
Highly Cited
1994
Highly Cited
1994
Effects of interleukin-3 and c-kit ligand on the survival of various classes of human hematopoietic progenitor cells.
We examined the effects of interleukin-3 (IL-3) and c-kit ligand (KL) on the survival of differentiated hematopoietic progenitor… 
Highly Cited
1994
Highly Cited
1994
Induction of IL-3 and granulocyte-macrophage colony-stimulating factor by substance P in bone marrow cells is partially mediated through the release of IL-1 and IL-6.
Experimental data strongly suggest that the nervous and immune systems are interrelated. One example of this interrelation is… 
Highly Cited
1993
Highly Cited
1993
Cell surface site for mitogenic interaction of erythropoietin receptors with the membrane glycoprotein encoded by Friend erythroleukemia virus.
Highly Cited
1990
Highly Cited
1990
Cloning and expression of a gene encoding an interleukin 3 receptor-like protein: identification of another member of the cytokine receptor gene family.
Using a monoclonal antibody to the interleukin 3 (IL-3) receptor (anti-Aic2), we isolated a cDNA (AIC2B) from a mouse mast cell… 
Highly Cited
1989
Highly Cited
1989
Vaccination against murine cutaneous leishmaniasis by using Leishmania major antigen/liposomes. Optimization and assessment of the requirement for intravenous immunization.
Efficacy of vaccination against cutaneous leishmaniasis in highly susceptible BALB/c mice was assessed comparatively by using… 
Highly Cited
1988
Highly Cited
1988
Amplification of IL-2-driven T cell proliferation by recombinant human IL-3 and granulocyte-macrophage colony-stimulating factor.
Two recombinant human preparations of CSF, namely granulocyte-macrophage-CSF (GM-CSF) and IL-3 (multi-CSF), were tested for their… 
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