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daniplestim
A synthetic cytokine and interleukin-3 (IL-3) receptor agonist with enhanced hematopoietic potency. Daniplestim exhibits 10- to 20-fold greater…
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National Institutes of Health
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Related topics
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6 relations
Inhibition of Cell Proliferation
Interleukin-3 Receptor
analogs & derivatives
Broader (2)
Interleukin-3
Peptide Fragments
Narrower (1)
SC 55494
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2010
2010
Transdermal delivery of a ~13 kDa protein—an in vivo comparison of physical enhancement methods
S. Katikaneni
,
Guohua Li
,
A. Badkar
,
A. Banga
Journal of drug targeting
2010
Corpus ID: 6649066
The availability of several enhancement techniques has made it possible to study delivery of macromolecules through skin. This…
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2009
2009
Molecular charge mediated transport of a 13 kD protein across microporated skin.
S. Katikaneni
,
A. Badkar
,
S. Nema
,
A. Banga
International journal of pharmaceutics
2009
Corpus ID: 19413378
2001
2001
Enhanced ability of daniplestim and myelopoietin-1 to suppress apoptosis in human hematopoietic cells
J. McCubrey
,
W. Blalock
,
+9 authors
J. McKearn
Leukemia
2001
Corpus ID: 7316051
Modified and chimeric cytokines have been developed to aid in the recovery of hematopoietic precursor cells after myeloablative…
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2000
2000
Effective ex vivo generation of granulopoietic postprogenitor cells from mobilized peripheral blood CD34(+) cells.
S. Scheding
,
B. Meister
,
+5 authors
W. Brugger
Experimental hematology
2000
Corpus ID: 2549773
2000
2000
Mobilization of peripheral-blood stem cells by concurrent administration of daniplestim and granulocyte colony-stimulating factor in patients with breast cancer or lymphoma.
J. Dipersio
,
M. Schuster
,
+5 authors
C. Baum
Journal of clinical oncology : official journal…
2000
Corpus ID: 42024879
PURPOSE To evaluate the safety and hematopoietic activity of daniplestim administered concurrently with granulocyte colony…
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2000
2000
Clinical-scale production of granulocyte progenitor and post-progenitor cells using daniplestim, leridistim, Progenipoietin, Promegapoietin and autologous plasma.
S. Patel
,
R. Guo
,
+4 authors
J. Winter
Cytotherapy
2000
Corpus ID: 40233140
BACKGROUND Supplementation of PBPC autografts with ex vivo expanded PBMC may significantly reduce or eliminate the period of…
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1999
1999
Myelopoietin, a chimeric agonist of human interleukin 3 and granulocyte colony-stimulating factor receptors, mobilizes CD34+ cells that rapidly engraft lethally x-irradiated nonhuman primates.
T. MacVittie
,
A. Farese
,
T. Davis
,
L. Lind
,
J. Mckearn
Experimental hematology
1999
Corpus ID: 28446350
1999
1999
Administration of daniplestim and granulocyte colony-stimulating factor for the mobilization of hematopoietic progenitor cells in nonhuman primates.
W. Fleming
,
P. Lankford-Turner
,
C. Turner
,
J. Wong
,
E. Strobert
,
J. Mckearn
Biology of blood and marrow transplantation…
1999
Corpus ID: 11694147
We investigated the effects of administering a high-affinity interleukin-3 receptor agonist (daniplestim) and granulocyte colony…
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1999
1999
Evaluation of refolding conditions for a recombinant human interleukin‐3 variant (daniplestim)
D. M. Boyle
,
R. E. McKinnie
,
W. Joy
,
B. Violand
,
J. K. Mclaughlin
,
B. Landis
Biotechnology and applied biochemistry
1999
Corpus ID: 27928416
The refolding of daniplestim, a human interleukin‐3 variant (SC‐55494) from Escherichia coli inclusion bodies, was optimized…
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1998
1998
The combined administration of daniplestim and mpl ligand augments the hematopoietic reconstitution observed with single cytokine administration in a nonhuman primate model of myelosuppression
A. Farese
,
T. MacVittie
,
L. Lind
,
W. Smith
,
J. Mckearn
Stem cells
1998
Corpus ID: 33068501
This study evaluated the ability of daniplestim, a high affinity interleukin 3 receptor agonist, to enhance the hematopoietic…
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