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daniplestim

A synthetic cytokine and interleukin-3 (IL-3) receptor agonist with enhanced hematopoietic potency. Daniplestim exhibits 10- to 20-fold greater… 
National Institutes of Health

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6 relations
Inhibition of Cell ProliferationInterleukin-3 Receptoranalogs & derivatives

Broader (2)

Interleukin-3Peptide Fragments

Narrower (1)

SC 55494

Papers overview

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2011
2011
Iontophoresis of a 13 kDa protein monitored by subcutaneous microdialysis in vivo.
BACKGROUND The purpose of this study was to optimize parameters pertaining to microdialysis technique so as to make this method… 
2009
2009
Molecular charge mediated transport of a 13 kD protein across microporated skin.
2009
2009
Transdermal delivery of a ~13 kDa protein—an in vivo comparison of physical enhancement methods
The availability of several enhancement techniques has made it possible to study delivery of macromolecules through skin. This… 
2001
2001
Enhanced ability of daniplestim and myelopoietin-1 to suppress apoptosis in human hematopoietic cells
Modified and chimeric cytokines have been developed to aid in the recovery of hematopoietic precursor cells after myeloablative… 
2000
2000
Effective ex vivo generation of granulopoietic postprogenitor cells from mobilized peripheral blood CD34(+) cells.
2000
2000
Clinical-scale production of granulocyte progenitor and post-progenitor cells using daniplestim, leridistim, Progenipoietin, Promegapoietin and autologous plasma.
BACKGROUND Supplementation of PBPC autografts with ex vivo expanded PBMC may significantly reduce or eliminate the period of… 
2000
2000
Enhanced ability of daniplestim and mpo-1 to suppress apoptosis and stimulate cytokine-inducible gene expression
1999
1999
Administration of daniplestim and granulocyte colony-stimulating factor for the mobilization of hematopoietic progenitor cells in nonhuman primates.
We investigated the effects of administering a high-affinity interleukin-3 receptor agonist (daniplestim) and granulocyte colony… 
Review
1999
Review
1999
[New cytokines and their role in supportive care].
Several cytokines stimulating hematopoiesis, mainly lineage restricted, are already widely used in supportive care to correct… 
1998
1998
The combined administration of daniplestim and mpl ligand augments the hematopoietic reconstitution observed with single cytokine administration in a nonhuman primate model of myelosuppression
This study evaluated the ability of daniplestim, a high affinity interleukin 3 receptor agonist, to enhance the hematopoietic… 
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