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IL2RA gene

Known as: IL2R, TAC ANTIGEN, CD25 
This gene plays a role in clathrin-independent endocytosis and immune functions.
National Institutes of Health

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Related topics

10 relations
Antigens, CD25Cytokine Signaling ProcessIL2RA protein, humanImmune System Processes

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IL2RA wt Allele

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
The multiple sclerosis susceptibility genes TAGAP and IL2RA are regulated by vitamin D in CD4+ T cells
Multiple sclerosis (MS) is an inflammatory, demyelinating disorder of the central nervous system that develops in genetically… 
Highly Cited
2014
Highly Cited
2014
Feature ranking of type 1 diabetes susceptibility genes improves prediction of type 1 diabetes
Aims/hypothesisMore than 40 regions of the human genome confer susceptibility for type 1 diabetes and could be used to establish… 
2014
2014
Association of IL-2RA and IL-2RB genes with erosive status in early rheumatoid arthritis patients (ESPOIR and RMP cohorts).
Highly Cited
2013
Highly Cited
2013
Human IL2RA null mutation mediates immunodeficiency with lymphoproliferation and autoimmunity
2013
2013
Association of variants in IL2RA with progression of joint destruction in rheumatoid arthritis.
OBJECTIVE Heritability studies have suggested an important role of genetic predisposition in the progression of joint destruction… 
2013
2013
CpG Methylation Changes within the IL2RA Promoter in Type 1 Diabetes of Childhood Onset
None of the polymorphic variants of the IL2RA gene found associated with Type 1 Diabetes (T1D) was shown to have a functional… 
2011
2011
Analysis of the HLA and non‐HLA susceptibility loci in Japanese type 1 diabetes
We previously reported the associations of human leukocyte antigen (HLA) (DRB1 and DQB1), INS, CTLA4, IL2RA, ERBB3 and CLEC16A… 
Highly Cited
2009
Highly Cited
2009
Contrasting genetic association of IL2RA with SLE and ANCA – associated vasculitis
BackgroundAutoimmune diseases are complex and have genetic and environmental susceptibility factors. The objective was to test… 
2009
2009
The type I diabetes association of the IL2RA locus
To confirm and fine map previous reports of association, the Type I Diabetes (T1D) Genetics Consortium (T1DGC) assembled a large… 
2009
2009
A cis-Acting Regulatory Variant in the IL2RA Locus1
The mechanism for the association of type 1 diabetes (T1D) with IL2RA remains to be clarified. Neither of the two distinct… 
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