IL2RA protein, human

Known as: IL2R, TAC Antigen, CD25 
Interleukin-2 receptor subunit alpha (272 aa, ~31 kDa) is encoded by the human IL2RA gene. This protein plays a role in interleukin-2-dependent… (More)
National Institutes of Health

Papers overview

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Highly Cited
2009
Highly Cited
2009
Genome-wide association studies (GWAS) have identified over 300 regions associated with more than 70 common diseases. However… (More)
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Highly Cited
2009
Highly Cited
2009
Multiple sclerosis (MS) and type 1 diabetes (T1D) are organ-specific autoimmune disorders with significant heritability, part of… (More)
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Highly Cited
2008
Highly Cited
2008
A recent genome-wide association study (GWAS) conducted by the International Multiple Sclerosis Genetics Consortium (IMSGC… (More)
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Highly Cited
2007
Highly Cited
2007
Genome-wide association studies are now identifying disease-associated chromosome regions. However, even after convincing… (More)
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Highly Cited
2001
Highly Cited
2001
CD4(+)CD25(+) T cells have been identified as a population of immunoregulatory T cells, which mediate suppression of CD4(+)CD25… (More)
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Highly Cited
2001
Highly Cited
2001
Therapeutic efficacy of a tumor cell-based vaccine against experimental B16 melanoma requires the disruption of either of two… (More)
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Highly Cited
2000
Highly Cited
2000
It is now clear that functionally specialized regulatory T (Treg) cells exist as part of the normal immune repertoire, preventing… (More)
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Highly Cited
2000
Highly Cited
2000
This report shows that cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) plays a key role in T cell-mediated dominant… (More)
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Highly Cited
1995
Highly Cited
1995
Interleukins-2 and -15 (IL-2 and IL-15) are cytokines with overlapping but distinct biological effects. Their receptors share two… (More)
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Highly Cited
1992
Highly Cited
1992
Partial complexes of the T cell antigen receptor lacking zeta chains are delivered to lysosomes. Chimeric proteins composed of… (More)
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