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IL2RA protein, human

Known as: IL2R, TAC Antigen, CD25 
Interleukin-2 receptor subunit alpha (272 aa, ~31 kDa) is encoded by the human IL2RA gene. This protein plays a role in interleukin-2-dependent… 
National Institutes of Health

Related topics

Related topics

25 relations

Broader (2)

Antigens, CD25Interleukin 2 Receptor, Alpha
ApoptosisB3(Fv)-PE38KDEL recombinant immunotoxinCell ProliferationCytokine Receptor Gene

Papers overview

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1987
1987
Evidence for negative regulation of T cell growth by low affinity interleukin 2 receptors.
Two experimental situations have been studied, and the results provide evidence for a negative regulatory role for the low… 
1987
1987
Antigen-specific and -nonspecific mitogenic signals in the activation of human T cell clones.
We have directly compared the signals required for: induction of the [Ca+2]i response, expression of Tac antigen, and… 
1986
1986
Expression and function of an early activation marker restricted to human B cells.
A B cell-specific monoclonal antibody (anti-Ba) was prepared. In two-color FACS analysis the anti-Ba reacted with a subpopulation… 
1986
1986
Delineation and characterization of human B cell subpopulations at various stages of activation by using a B cell-specific monoclonal antibody.
Human tonsillar B cells were separated into three distinct subpopulations, Ba-/IgD+, Ba+/IgD+, and Ba+/IgD-, by using a B cell… 
1985
1985
In vitro maturation of B cells in chronic lymphocytic leukemia. I. Synergistic action of phorbol ester and interleukin 2 in the induction of Tac antigen expression and interleukin 2 responsiveness in…
Recent evidence indicates that interleukin 2 (IL 2), formerly thought to serve as growth factor exclusively for activated T cells… 
1985
1985
Two mouse monoclonal antibodies detecting two different epitopes of an activated lymphocyte antigen on adult T-cell leukemia cells.
Mouse monoclonal antibodies were produced against MT-2 cell line derived from adult T-cell leukemia or human T-cell leukemia… 
1984
1984
Culture and Phenotype of Activated T-Cells from Patients with Type I Diabetes Mellitus
Blood T-cells from 28 patients with type I (insulin-dependent) diabetes (IDDM) of variable duration were examined for the Tac… 
1984
1984
Phorbol diester induces expression of Tac antigen on human acute T lymphocytic leukemic cells.
In general, the human acute T lymphocytic leukemias are composed of malignant expansions of immature T cells lacking membrane… 
1984
1984
Dissociation in the production of B cell-stimulating factors (BCGF and BCDF) and interleukin 2 by T cells from a common variable immunodeficient patient.
In the course of an analysis of lymphocyte functions of common variable immunodeficiency patients, we found one patient whose T… 
1983
1983
Kinetics of expression of T-cell "activation" antigens on in vivo- and in vitro-stimulated T cells.
The in vivo expression of T-cell activation antigens defined by means of an OKT series of monoclonal antibodies and the anti-Tac…