Skip to search formSkip to main contentSkip to account menu

Interleukin 2 Receptor, Alpha

Known as: IL 2Ralpha, Interleukin-2Ralpha, CD25 Antigens 
A low affinity interleukin-2 receptor subunit that combines with the INTERLEUKIN-2 RECEPTOR BETA SUBUNIT and the INTERLEUKIN RECEPTOR COMMON GAMMA… 
National Institutes of Health

Related topics

Related topics

12 relations

Broader (1)

Antigens, CD25
IL2RA geneIL2RA wt AlleleIn BloodInterleukin 2 Receptor

Narrower (2)

IL2RA protein, humanInterleukin 2 Receptor, Alpha, Deficiency of

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2009
2009
CD4+ T Cell-Derived IL-2 Signals during Early Priming Advances Primary CD8+ T Cell Responses
Stimulating naïve CD8+ T cells with specific antigens and costimulatory signals is insufficient to induce optimal clonal… 
Highly Cited
2006
Highly Cited
2006
Correction of interleukin-2 gene expression by in vitro zinc addition to mononuclear cells from zinc-deficient human subjects: a specific test for zinc deficiency in humans.
2001
2001
Studies Using Leukemia Inhibitory Factor (LIF) Knockout Mice and a LIF Adenoviral Vector Demonstrate a Key Anti-Inflammatory Role for This Cytokine in Cutaneous Inflammation1
Previous work has implicated the cytokine leukemia inhibitory factor (LIF) in cutaneous inflammation, although results have… 
Highly Cited
1999
Highly Cited
1999
CD28, IL-2-independent costimulatory pathways for CD8 T lymphocyte activation.
We investigate, here, the mechanism of the costimulatory signals for CD8 T cell activation and confirm that costimulation signals… 
Highly Cited
1998
Highly Cited
1998
Altered receptor expression and decreased sensitivity of T-cells to the stimulatory cytokines IL-2, IL-7 and IL-12 in HIV infection.
Highly Cited
1997
Highly Cited
1997
In vitro interleukin 12 activation of peripheral blood CD3(+)CD56(+) and CD3(+)CD56(-) gammadelta T cells from glioblastoma patients.
Interleukin (IL)-12 has recently been shown to be directly involved in the activation of natural killer and alphabeta T cells via… 
Highly Cited
1995
Highly Cited
1995
Distinct Functions of the FcεR1 γ and β Subunits in the Control of FcεR1-mediated Tyrosine Kinase Activation and Signaling Responses in RBL-2H3 Mast Cells (*)
In RBL-2H3 rat tumor mast cells, cross-linking the high affinity IgE receptor, FcεR1, activates the protein-tyrosine kinases Lyn… 
1993
1993
High serum and ascitic soluble interleukin-2 receptor alpha levels in advanced epithelial ovarian cancer.
This study was undertaken to determine if advanced epithelial ovarian cancer was associated with increased serum and ascitic… 
Highly Cited
1992
Highly Cited
1992
Kappa B site-dependent activation of the interleukin-2 receptor alpha-chain gene promoter by human c-Rel
The cis-acting control elements of the interleukin-2 receptor alpha-chain (IL-2R alpha) gene contain a potent kappa B-like… 
Highly Cited
1990
Highly Cited
1990
Development of immature thymocytes: initiation of CD3, CD4, and CD8 acquisition parallels down‐regulation of the interleukin 2 receptor α chain
We have previously identified a developmental sequence among immature thymocytes, prior to their expression of the lineage… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)