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Interleukin 2 Receptor, Alpha

Known as: IL 2Ralpha, Interleukin-2Ralpha, CD25 Antigens 
A low affinity interleukin-2 receptor subunit that combines with the INTERLEUKIN-2 RECEPTOR BETA SUBUNIT and the INTERLEUKIN RECEPTOR COMMON GAMMA… Expand
National Institutes of Health

Papers overview

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Highly Cited
2010
Highly Cited
2010
Interleukin(IL)-2 and inflammation regulate effector and memory cytolytic T-lymphocyte (CTL) generation during infection. We… Expand
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Highly Cited
2007
Highly Cited
2007
BACKGROUND Multiple sclerosis has a clinically significant heritable component. We conducted a genomewide association study to… Expand
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Highly Cited
2007
Highly Cited
2007
OBJECTIVE Macrophage activation syndrome is characterized by an overwhelming inflammatory reaction driven by excessive expansion… Expand
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Highly Cited
2006
Highly Cited
2006
Administration of daclizumab, a humanized mAb directed against the IL-2Ralpha chain, strongly reduces brain inflammation in… Expand
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Highly Cited
2005
Highly Cited
2005
Interleukin-2 (IL-2) is an immunoregulatory cytokine that binds sequentially to the alpha (IL-2Rα), beta (IL-2Rβ), and common… Expand
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Highly Cited
2004
Highly Cited
2004
GITR (glucocorticoid-induced TNFR family related gene) is a member of the TNFR superfamily (TNFRSF) that is expressed in… Expand
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Highly Cited
2002
Highly Cited
2002
We show that the lymphoid hyperplasia observed in IL-2Rα- and IL-2-deficient mice is due to the lack of a population of… Expand
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Highly Cited
2001
Highly Cited
2001
CD4+CD25+ regulatory T cells inhibit organ-specific autoimmune diseases induced by CD4+CD25− T cells and are potent suppressors… Expand
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Highly Cited
1999
Highly Cited
1999
Immune regulation has been shown to be involved in the progressive growth of some murine tumors. In this study, we demonstrated… Expand
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Highly Cited
1997
Highly Cited
1997
Profound cellular immunodeficiency occurs as the result of mutations in proteins involved in both the differentiation and… Expand
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