IFNL4 gene

Known as: IFNAN, IFNL4, INTERFERON, LAMBDA-4 
This gene plays a role in antiviral responses and JAK-STAT pathway activation.
National Institutes of Health

Papers overview

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2015
2015
BACKGROUND & AIMS Genetic polymorphisms within the interferon lambda (IFN-λ) region are strongly associated with hepatitis C… (More)
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2014
2014
Response to pegylated interferon-alpha and ribavirin (IFN-α/RBV) treatment for chronic hepatitis C virus (HCV) infection is… (More)
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2014
2014
Interferon lambda 4 gene (IFNL4) encodes IFN-λ4, a new member of the IFN-λ family with antiviral activity. In humans IFNL4 open… (More)
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2014
2014
A new type III interferon, IFN lambda 4 (IFNL4), and its single-nucleotide polymorphism (SNP) ss469415590 causing a frame shift… (More)
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2014
2014
OBJECTIVES The rs12979860 variant, linked to IL28B gene, predicts sustained viral response (SVR) to pegylated-interferon… (More)
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2014
2014
BACKGROUND About 30% of individuals with hepatitis C virus (HCV) infection are able to clear HCV spontaneously. Differences in… (More)
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Highly Cited
2013
Highly Cited
2013
Chronic infection with hepatitis C virus (HCV) is a common cause of liver cirrhosis and cancer. We performed RNA sequencing in… (More)
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2013
2013
Eradication of hepatitis C virus (HCV) infection, both spontaneous and treatment-induced, is marked by the wildtype allele C of a… (More)
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2013
2013
Older patients with chronic hepatitis C have a lower virological response to interferon (IFN) treatment compared to younger… (More)
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