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IFNGR1 protein, human

Known as: IFN-Gamma-R1, IFN-Gamma Receptor 1, Interferon Gamma Receptor-1 
Interferon gamma receptor 1 (489 aa, ~54 kDa) is encoded by the human IFNGR1 gene. This protein plays a role in inteferon-gamma-mediated signaling.
National Institutes of Health

Related topics

Related topics

18 relations
Antiviral ResponseCytokine Receptor GeneCytokine Signaling ProcessIFNGR1 gene

Broader (1)

interferon gamma receptor

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
Dysregulation of JAK/STAT genes by vasoactive intestinal peptide (VIP) in Salmonella‐infected monocytes may inhibit its therapeutic potential in human sepsis
2016
2016
The importance of single nucleotide polymorphisms in interferon gamma receptor-1 gene in pulmonary patients infected with rapid grower mycobacterium
2004
2004
Interferon-gamma receptor 1 promoter polymorphisms: population distribution and functional implications.
Different polymorphisms have been described in the minimal promoter region (MPR) of the interferon-gamma receptor 1 (IFNGR1), a… 
2003
2003
Missense mutations of the interleukin-12 receptor beta 1(IL12RB1) and interferon-gamma receptor 1 (IFNGR1) genes are not associated with susceptibility to lepromatous leprosy in Korea
Interleukin-12 receptor beta 1 (IL12RB1), interleukin-12 receptor beta 2 (IL12RB2), and interferon gamma receptor 1 (IFNGR1… 
Highly Cited
2002
Highly Cited
2002
Genetic basis of patients with bacille Calmette-Guérin osteomyelitis in Japan: identification of dominant partial interferon-gamma receptor 1 deficiency as a predominant type.
Interferon (IFN)-gamma-mediated immunity plays an important role in host defense against intracellular pathogens, especially… 
2002
2002
561del4 defines a novel small deletion hotspot in the interferon-gamma receptor 1 chain.
Patients with a dominant small deletion (818del4, hotspot) in the interferon-gamma receptor 1 (IFNGR1) gene (6q23-q24) and… 
2000
2000
Interleukin-12 Neutralization Alters Lung Inflammation and Leukocyte Expression of CD80, CD86, and Major Histocompatibility Complex Class II in Mice Infected withHistoplasma capsulatum
ABSTRACT Histoplasma capsulatum induces a cell-mediated immune response in lungs and lymphoid organs of mammals. Resolution of… 
1995
1995
Mutagenesis of immunoglobulin-like domains from the extracellular human interferon-gamma receptor alpha chain and their recognition by neutralizing antibodies monitored by surface plasmon resonance…
1988
1988
Immune interferon receptor: chemical and enzymatic sensitivity.
Human immune interferon-gamma (HuIFN-gamma) labeled with 32P was used to study the structure of IFN-gamma receptor. When [32P… 
1986
1986
Preparation of 32P-labeled murine immune interferon and its binding to the mouse immune interferon receptor.
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