Skip to search formSkip to main contentSkip to account menu

IFNAR1 wt Allele

Known as: Interferon (Alpha, Beta and Omega) Receptor 1 wt Allele, IFNABR, IFNBR 
Human IFNAR1 wild-type allele is located in the vicinity of 21q22.11 and is approximately 35 kb in length. This allele, which encodes interferon… 
National Institutes of Health

Related topics

Related topics

12 relations
21q22.1Antiviral ResponseBone Remodelling PathwayCytokine Signaling Process

Broader (1)

AVP gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2012
2012
Lithium Controls Central Nervous System Autoimmunity through Modulation of IFN-γ Signaling
Inhibitors of glycogen synthase kinase 3 (GSK3) are being explored as therapy for chronic inflammatory diseases. We previously… 
2011
2011
One-year evaluation of factors affecting the biological activity of interferon beta in multiple sclerosis patients
MxA is an antiviral protein induced by type I interferons (IFN) and some viruses; MxA gene expression is an appropriate marker… 
2011
2011
Both Nonstructural Proteins NS1 and NS2 of Pneumonia Virus of Mice are Inhibitors of the Interferon Type I and Type III Responses In Vivo
ABSTRACT Infection of mice with pneumonia virus of mice (PVM) provides a convenient experimental pathogenesis model in a natural… 
Highly Cited
2007
Highly Cited
2007
Establishment of a Poliovirus Oral Infection System in Human Poliovirus Receptor-Expressing Transgenic Mice That Are Deficient in Alpha/Beta Interferon Receptor
ABSTRACT Poliovirus (PV) is easily transferred to humans orally; however, no rodent model for oral infections has been developed… 
2007
2007
Stronger growth-inhibitory effect of interferon (IFN)-beta compared to IFN-alpha is mediated by IFN signaling pathway in hepatocellular carcinoma cells.
Interferon (IFN) is a promising drug for prevention and treatment of hepatocellular carcinoma (HCC) in combination with… 
2005
2005
IL-12, but Not IFN-α, Promotes STAT4 Activation and Th1 Development in Murine CD4+ T Cells Expressing a Chimeric Murine/Human Stat2 Gene1
Humans and mice have evolved distinct pathways for Th1 cell development. Although IL-12 promotes CD4+ Th1 development in both… 
2001
2001
Novel IFN-α receptor promoter polymorphisms
We have identified two single nucleotide polymorphisms and one dinucleotide microsatellite within the promoter region of the… 
1999
1999
IFN-alpha receptor mRNA expression in a United States sample with predominantly genotype 1a/I chronic hepatitis C liver biopsies correlates with response to IFN therapy.
Our aim was to assess whether, in the United States, with the predominant hepatitis C viral (HCV) genotypes 1a/I and 1b/II… 
1994
1994
A gene on human chromosome 21 located in the region 21q22.2 to 21q22.3 encodes a factor necessary for signal transduction and antiviral response to type I interferons.
1992
1992
Specific antiviral activities of the human α interferons are determined at the level of receptor (IFNAR) structure
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)