IEM 1754

Known as: IEM-1754 
 
National Institutes of Health

Papers overview

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2008
2008
There is numerous experimental and conceptual proof that the extracellular portion of ionotropic glutamate receptors (iGluRs), i… Expand
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2000
2000
1. The kinetics of open channel block of GluR2-containing and GluR2-lacking AMPA receptors (AMPAR) by dicationic compounds (IEM… Expand
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2000
2000
Pyrilene acts as a central H-cholinoblocker upon intramuscular injection at a dose of 0.02-0.08 mg/kg, and as an NMDA-blocker… Expand
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2000
2000
A long-term akinesia induced by haloperidol used as an experimental model of catalepsy helped to reveal that a dicationic… Expand
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2000
2000
Two groups of substances capable of selectively blocking the NMDA and AMPA/kainate receptors in experiments on intact animals… Expand
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1998
1998
We report the presence of binding sites for permeant monovalent cations at the internal and external entrances to the channel of… Expand
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Highly Cited
1997
Highly Cited
1997
1. The effects of two adamantane derivatives, 1-trimethylammonio-5-(1-adamantane-methyl-ammoniopentane dibromide) (IEM-1460) and… Expand
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1997
1997
The action of three dicationic drugs, derivatives of adamantane (IEM-1460 and IEM-1754) and phencyclidine (IEM-1925), on… Expand
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1996
1996
1. The mechanisms by which four adamantane derivatives (IEM-1857, -1592, -1460 and -1754) block the open NMDA-activated channel… Expand
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1995
1995
We examined the influence of the molecular structure of four novel adamantane derivatives on their ability to block the channels… Expand
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