ICR-191
National Institutes of Health
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Human TK6 lymphoblasts were treated with the acridine derivative ICR‐191, and mutants at the hprt locus were isolated. Mutant…
ICR-191, an acridine half-mustard known to cause frameshift mutations in bacteria, was used to induce Lac− mutations revertible…
The system previously described for inducing single gene mutations in Chinese hamster cells has been extended to produce…