ICI 207968

Known as: ICI-207968, ICI207968 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

1990-1996
01219901996

Papers overview

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1996
1996
Inflammatory mediators have been implicated in the pathophysiology of ulcerative colitis. They may stimulate intestinal secretion… (More)
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1994
1994
1. Biopsies of colonic mucosa from patients with ulcerative colitis liberated more interleukin-1 beta, prostaglandin E2… (More)
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1993
1993
Metabolites of arachidonic acid have been implicated in the pathophysiology of ulcerative colitis-they can stimulate intestinal… (More)
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1991
1991
Since the hypothetical mechanisms of hydroperoxydation of arachidonic acid by, respectively, 5-lipoxygenase (5-LPO) and… (More)
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1991
1991
TNF is a potent cytokine which can induce many of the pathological changes associated with inflammatory disease.In vitro studies… (More)
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1990
1990
1. This paper describes the pharmacological profile of ICI207968, a novel, orally-active and selective inhibitor of 5… (More)
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1990
1990
The objective of this work was to investigate the role of leukotrienes in the production of IL-1 by activated human peripheral… (More)
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