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Use of coculture of colonic mucosal biopsies to investigate the release of eicosanoids by inflamed and uninflamed mucosa from patients with inflammatory bowel disease.
Eicosanoid production was measured in cultured biopsies of colonic mucosa from control patients, with the irritable bowel syndrome, and from patients with proctosigmoiditis and with colonic Crohn'sExpand
Platelet activating factor: release from colonic mucosa in patients with ulcerative colitis and its effect on colonic secretion.
Inflammatory mediators have been implicated in the pathophysiology of ulcerative colitis. They may stimulate intestinal secretion and contribute to the production of diarrhoea. Platelet activatingExpand
Potential role for interleukin-1 in the pathophysiology of ulcerative colitis.
1. Biopsies of colonic mucosa from patients with ulcerative colitis liberated more interleukin-1 beta, prostaglandin E2, leukotriene C4 and platelet-activating factor into the medium in which theyExpand
Influence of atrial natriuretic peptide on mammalian large intestine.
Atrial natriuretic peptide is distributed in a number of organs including the large intestine. Atrial natriuretic peptide has potent diuretic and natriuretic properties and appears to play a centralExpand
Inter-relationships between inflammatory mediators released from colonic mucosa in ulcerative colitis and their effects on colonic secretion.
Metabolites of arachidonic acid have been implicated in the pathophysiology of ulcerative colitis-they can stimulate intestinal secretion, increase mucosal blood flow, and influence smooth muscleExpand
Plasmodium falciparum and hepatitis B virus co-infection – a rare cause of acute hepatitis To the
I read with great interest the recent paper by Sanada and Yoshida on benign intraductal papillary mucinous neoplasm (IPMN) of the pancreas containing two major subtypes [1]. In this case report theExpand
Metastasis of ulcerative colitis in peristomal skin--an extremely rare case.
Extra-intestinal complications affect 20-30% of patients with Ulcerative Colitis and contribute significantly to morbidity and mortality. While some disorders parallel the activity of the colitis,Expand