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ICA1 protein, human

Known as: ICA 69 protein, human, ICA69 protein, human, islet cell antigen p69 protein, human 
National Institutes of Health

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Broader (1)

Autoantigens
ICA1 gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2012
Review
2012
Islet autoantigens: structure, function, localization, and regulation.
Islet autoantigens associated with autoimmune type 1 diabetes (T1D) are expressed in pancreatic β cells, although many show wider… 
Highly Cited
2009
Highly Cited
2009
UNC-108/RAB-2 and its effector RIC-19 are involved in dense core vesicle maturation in Caenorhabditis elegans
Uncoordinated movement in Rab2 mutants is caused by impaired retention of cargo on dense core vesicles, not by defective synaptic… 
Highly Cited
2005
Highly Cited
2005
Identification of proteins released by pancreatic cancer cells by multidimensional protein identification technology: a strategy for identification of novel cancer markers
The purpose of this study is to identify novel proteins released by cancer cells that are involved in extracellular matrix (ECM… 
2003
2003
Reduced Thymic Expression of Islet Antigen Contributes to Loss of Self‐Tolerance
Abstract: Type 1 diabetes (T1DM) results from a failure of central and peripheral tolerance to islet cell antigens. ICA69 belongs… 
Highly Cited
2002
Highly Cited
2002
Primary Sjögren's syndrome and deficiency of ICA69
2002
2002
ICA69null Nonobese Diabetic Mice Develop Diabetes, but Resist Disease Acceleration by Cyclophosphamide1
ICA69 (islet cell Ag 69 kDa) is a diabetes-associated autoantigen with high expression levels in β cells and brain. Its function… 
2002
2002
Lymphoid organs contain diverse cells expressing self-molecules
• april 2002 • volume 3 no 4 • nature immunology 335 Data reported by Derbinski et al. 1 reinforce the concept that thymic cells… 
Highly Cited
1997
Highly Cited
1997
Immunological Aspects of Nutritional Diabetes Prevention in NOD Mice: A Pilot Study for the Cow's Milk–Based IDDM Prevention Trial
Human epidemiological studies delineated early exposure to intact dietary protein (e.g., most infant formulas) as an… 
1996
1996
ICA69 is expressed equally in the human endocrine and exocrine pancreas
SummaryIslet cell autoantigen 69 kDa (ICA69) has been reported as a polypeptide antigen expressed in pancreatic beta cells, and… 
1994
1994
Sera from patients with IDDM and healthy individuals have antibodies to ICA69 on western blots but do not immunoprecipitate liquid phase antigen.
ICA69 is a recently cloned pancreatic islet protein proposed as a potential target of autoimmunity in insulin dependent diabetes… 
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