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ICA1 protein, human

Known as: ICA 69 protein, human, ICA69 protein, human, islet cell antigen p69 protein, human 
 
National Institutes of Health

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Related topics

2 relations

Broader (1)

Autoantigens
ICA1 gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2013
2013
PICK1 Deficiency Impairs Secretory Vesicle Biogenesis and Leads to Growth Retardation and Decreased Glucose Tolerance
Secretory vesicles in endocrine cells store hormones such as growth hormone (GH) and insulin before their release into the… Expand
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2013
2013
PICK1 and ICA69 Control Insulin Granule Trafficking and Their Deficiencies Lead to Impaired Glucose Tolerance
Diabetes is a metabolic disorder characterized by hyperglycemia. Insulin, which is secreted by pancreatic beta cells, is… Expand
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Highly Cited
2009
Highly Cited
2009
UNC-108/RAB-2 and its effector RIC-19 are involved in dense core vesicle maturation in Caenorhabditis elegans
Small guanosine triphosphatases of the Rab family regulate intracellular vesicular trafficking. Rab2 is highly expressed in the… Expand
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Highly Cited
2005
Highly Cited
2005
Identification of proteins released by pancreatic cancer cells by multidimensional protein identification technology: a strategy for identification of novel cancer markers.
The purpose of this study is to identify novel proteins released by cancer cells that are involved in extracellular matrix (ECM… Expand
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2003
2003
A pancreatic beta-cell-specific homolog of glucose-6-phosphatase emerges as a major target of cell-mediated autoimmunity in diabetes.
Diabetes has been termed the epidemic of the 21st century and over the past 50 years in Western societies has been doubling in… Expand
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2002
2002
ICA69(null) nonobese diabetic mice develop diabetes, but resist disease acceleration by cyclophosphamide.
ICA69 (islet cell Ag 69 kDa) is a diabetes-associated autoantigen with high expression levels in beta cells and brain. Its… Expand
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1998
1998
Anti-BSA antibodies do not cross-react with the 69-kDa islet cell autoantigen ICA69.
In contrast to several previously published reports, we demonstrate by a variety of antibody assays that bovine serum albumin… Expand
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Highly Cited
1997
Highly Cited
1997
The insulin gene is transcribed in the human thymus and transcription levels correlate with allelic variation at the INS VNTR-IDDM2 susceptibility locus for type 1 diabetes
Type 1, or insulin-dependent diabetes mellitus (IDDM) is an autoimmune disease associated with loss of tolerance to several… Expand
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1997
1997
Immunological aspects of nutritional diabetes prevention in NOD mice: a pilot study for the cow's milk-based IDDM prevention trial.
Human epidemiological studies delineated early exposure to intact dietary protein (e.g., most infant formulas) as an… Expand
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1996
1996
HLA-associated inverse correlation between T cell and antibody responsiveness to islet autoantigen in recent-onset insulin-dependent diabetes mellitus.
Insulin-dependent diabetes mellitus (IDDM) is a T cell-dependent immune-mediated disease. Recently, a novel islet cell antigen… Expand
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