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ICA1 protein, human

Known as: ICA 69 protein, human, ICA69 protein, human, islet cell antigen p69 protein, human 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

1994-2017
012319942017

Related topics

Related topics

2 relations

Broader (1)

Autoantigens
ICA1 gene

Related mentions per year

Related mentions per year

1945-2018
19401960198020002020
ICA1 protein, human
Autoantigens
ICA1 gene

Papers overview

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2013
2013
PICK1 Deficiency Impairs Secretory Vesicle Biogenesis and Leads to Growth Retardation and Decreased Glucose Tolerance
Secretory vesicles in endocrine cells store hormones such as growth hormone (GH) and insulin before their release into the… (More)
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2013
2013
PICK1 and ICA69 Control Insulin Granule Trafficking and Their Deficiencies Lead to Impaired Glucose Tolerance
Diabetes is a metabolic disorder characterized by hyperglycemia. Insulin, which is secreted by pancreatic beta cells, is… (More)
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2007
2007
PICK1-ICA69 heteromeric BAR domain complex regulates synaptic targeting and surface expression of AMPA receptors.
The trafficking of AMPA-type glutamate receptors to and from synapses is an important mechanism underlying synaptic plasticity, a… (More)
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2005
2005
Identification of proteins released by pancreatic cancer cells by multidimensional protein identification technology: a strategy for identification of novel cancer markers.
The purpose of this study is to identify novel proteins released by cancer cells that are involved in extracellular matrix (ECM… (More)
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2003
2003
A pancreatic beta-cell-specific homolog of glucose-6-phosphatase emerges as a major target of cell-mediated autoimmunity in diabetes.
D iabetes has been termed the epidemic of the 21st century and over the past 50 years in Western societies has been doubling in… (More)
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2000
2000
The diabetes autoantigen ICA69 and its Caenorhabditis elegans homologue, ric-19, are conserved regulators of neuroendocrine secretion.
ICA69 is a diabetes autoantigen with no homologue of known function. Given that most diabetes autoantigens are associated with… (More)
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1999
1999
Persistent T cell anergy in human type 1 diabetes.
An anergic phenotype has been observed in nonobese diabetic (NOD) mice and some autoreactive T cells from patients with type I… (More)
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Highly Cited
1997
Highly Cited
1997
The insulin gene is transcribed in the human thymus and transcription levels correlate with allelic variation at the INS VNTR-IDDM2 susceptibility locus for type 1 diabetes
Type 1, or insulin-dependent diabetes mellitus (IDDM) is an autoimmune disease associated with loss of tolerance to several… (More)
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1997
1997
Immunological aspects of nutritional diabetes prevention in NOD mice: a pilot study for the cow's milk-based IDDM prevention trial.
Human epidemiological studies delineated early exposure to intact dietary protein (e.g., most infant formulas) as an… (More)
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1996
1996
HLA-associated inverse correlation between T cell and antibody responsiveness to islet autoantigen in recent-onset insulin-dependent diabetes mellitus.
Insulin-dependent diabetes mellitus (IDDM) is a T cell-dependent immune-mediated disease. Recently, a novel islet cell antigen… (More)
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