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ICA1 protein, human

Known as: ICA 69 protein, human, ICA69 protein, human, islet cell antigen p69 protein, human 
 
National Institutes of Health

Related topics

Related topics

2 relations

Broader (1)

Autoantigens
ICA1 gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2013
Highly Cited
2013
PICK1 Deficiency Impairs Secretory Vesicle Biogenesis and Leads to Growth Retardation and Decreased Glucose Tolerance
Two lipid membrane sculpting BAR domain proteins, PICK1 and ICA69, play a key role early in the biogenesis of peptide hormone… Expand
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Highly Cited
2013
Highly Cited
2013
PICK1 and ICA69 Control Insulin Granule Trafficking and Their Deficiencies Lead to Impaired Glucose Tolerance
PICK1 and ICA69, proteins containing a BAR domain, regulate the biogenesis and maturation of insulin granules in mice. 
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Review
2012
Review
2012
Islet autoantigens: structure, function, localization, and regulation.
Islet autoantigens associated with autoimmune type 1 diabetes (T1D) are expressed in pancreatic β cells, although many show wider… Expand
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Highly Cited
2009
Highly Cited
2009
UNC-108/RAB-2 and its effector RIC-19 are involved in dense core vesicle maturation in Caenorhabditis elegans
Uncoordinated movement in Rab2 mutants is caused by impaired retention of cargo on dense core vesicles, not by defective synaptic… Expand
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Highly Cited
2007
Highly Cited
2007
PICK1–ICA69 Heteromeric BAR Domain Complex Regulates Synaptic Targeting and Surface Expression of AMPA Receptors
The trafficking of AMPA-type glutamate receptors to and from synapses is an important mechanism underlying synaptic plasticity, a… Expand
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Highly Cited
2005
Highly Cited
2005
Identification of proteins released by pancreatic cancer cells by multidimensional protein identification technology: a strategy for identification of novel cancer markers
The purpose of this study is to identify novel proteins released by cancer cells that are involved in extracellular matrix (ECM… Expand
Highly Cited
2003
Highly Cited
2003
A pancreatic β-cell-specific homolog of glucose-6-phosphatase emerges as a major target of cell-mediated autoimmunity in diabetes
Diabetes has been termed the epidemic of the 21st century and over the past 50 years in Western societies has been doubling in… Expand
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Highly Cited
1997
Highly Cited
1997
The insulin gene is transcribed in the human thymus and transcription levels correlate with allelic variation at the INS VNTR-IDDM2 susceptibility locus for type 1 diabetes
Type 1, or insulin-dependent diabetes mellitus (IDDM) is an autoimmune disease associated with loss of tolerance to several… Expand
Highly Cited
1997
Highly Cited
1997
Immunological Aspects of Nutritional Diabetes Prevention in NOD Mice: A Pilot Study for the Cow's Milk–Based IDDM Prevention Trial
Human epidemiological studies delineated early exposure to intact dietary protein (e.g., most infant formulas) as an… Expand
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Highly Cited
1996
Highly Cited
1996
HLA‐associated inverse correlation between T cell and antibody responsiveness to islet autoantigen in recent‐onset insulin‐dependent diabetes mellitus
Insulin‐dependent diabetes mellitus (IDDM) is a T cell‐dependent immune‐mediated disease. Recently, a novel islet cell antigen… Expand
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