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ICA1 protein, human

Known as: ICA 69 protein, human, ICA69 protein, human, islet cell antigen p69 protein, human 
National Institutes of Health

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Broader (1)

Autoantigens
ICA1 gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
The dual role of autoimmune regulator in maintaining normal expression level of tissue-restricted autoantigen in the thymus: A modeling investigation.
2014
2014
PICK1 Mediates Synaptic Recruitment of AMPA Receptors at Neurexin-Induced Postsynaptic Sites
In the CNS, synapse formation and maturation play crucial roles in the construction and consolidation of neuronal circuits… 
2014
2014
Compromised central tolerance of ICA69 induces multiple organ autoimmunity.
2013
2013
A Pair of Crescent-shaped Proteins Shape Vesicles at the Golgi
Two membrane proteins containing a BAR domain, PICK1 and ICA69, regulate biogenesis and maturation of insulin granules in flies… 
2003
2003
Deviation of islet autoreactivity to cryptic epitopes protects NOD mice from diabetes
To better understand loss of self‐tolerance in diabetes‐prone NOD mice, we are generating ICA69 transgenes under control of the… 
2002
2002
ICA69null Nonobese Diabetic Mice Develop Diabetes, but Resist Disease Acceleration by Cyclophosphamide1
ICA69 (islet cell Ag 69 kDa) is a diabetes-associated autoantigen with high expression levels in β cells and brain. Its function… 
2002
2002
Lymphoid organs contain diverse cells expressing self-molecules
• april 2002 • volume 3 no 4 • nature immunology 335 Data reported by Derbinski et al. 1 reinforce the concept that thymic cells… 
2000
2000
Evidence for recognition of novel islet T cell antigens by granule‐specific T cell lines from new onset type 1 diabetic patients
Type 1 diabetes is a T cell‐mediated autoimmune disease where a number of islet β‐cell target autoantigens have been… 
1997
1997
Molecular cloning of murine ICA69: diabetes-prone mice recognize the human autoimmune-epitope, Tep69, conserved in splice variants from both species.
1997
1997
The identification of CD 4 1 T cell epitopes with dedicated synthetic peptide libraries ( insulin-dependent diabetes mellitus )
For a large number of T cell-mediated immunopathologies, the disease-related antigens are not yet identified. Identification of T… 
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