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ICA1 gene

Known as: ISLET CELL AUTOANTIGEN 1, ISLET CELL AUTOANTIGEN, 69-KD, ICA69 
National Institutes of Health

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ICA1 protein, human

Papers overview

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2013
2013
Scientia a Letter from Dean Crawford Editors-in-chief Photo Credits on the Front & Back Covers
Type 1 diabetes (T1D) is an autoimmune disorder that ultimately results in the complete destruction of insulin-producing… 
2010
2010
Sex-specific genetic dissection of diabetes in a rodent model identifies Ica1 and Ndufa4 as major candidate genes.
The aim of the study was to initiate a sex-specific investigation of the molecular basis of diabetes, using a genomic approach in… 
2007
2007
Modeling the Other Race Effect with ICA
Principal component analysis (PCA) learns the second-order dependencies be-tween image pixels, and performs information… 
2003
2003
Reduced Thymic Expression of Islet Antigen Contributes to Loss of Self‐Tolerance
Abstract: Type 1 diabetes (T1DM) results from a failure of central and peripheral tolerance to islet cell antigens. ICA69 belongs… 
2001
2001
Expression of GAD 65 and Islet Cell Antibody ( ICA 512 ) Autoantibodies Among Cytoplasmic ICA 1 Relatives Is Associated With Eligibility for the Diabetes Prevention Trial 2 Type 1
More than 71,000 relatives of type 1 diabetic patients have been screened for cytoplasmic islet cell antibodies (ICAs), GAD65… 
1998
1998
Anti-BSA antibodies do not cross-react with the 69-kDa islet cell autoantigen ICA69.
In contrast to several previously published reports, we demonstrate by a variety of antibody assays that bovine serum albumin… 
1996
1996
ICA69 is expressed equally in the human endocrine and exocrine pancreas
SummaryIslet cell autoantigen 69 kDa (ICA69) has been reported as a polypeptide antigen expressed in pancreatic beta cells, and… 
1994
1994
Sera from patients with IDDM and healthy individuals have antibodies to ICA69 on western blots but do not immunoprecipitate liquid phase antigen.
ICA69 is a recently cloned pancreatic islet protein proposed as a potential target of autoimmunity in insulin dependent diabetes… 
1994
1994
ICA1 encoding p69, a protein linked to the development of type 1 diabetes, maps to human chromosome 7p22.
The development of type 1 (insulin dependent) diabetes mellitus (IDDM) requires a genetically susceptible host and exposure… 
1983
1983
Evaluation of radiometer ICA1 as a routine instrument for serum ionized calcium and its application for whole blood capillary samples from newborn infants.
The Radiometer ICA1 was evaluated with four sets of samples: a) 289 serum samples sent for routine analysis of ionized calcium, b… 
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