Hypochlorous Acid

Hydrogen sulphide (H(2)S) is a cytotoxic gas that has recently been proposed as a novel neuromodulator. Endogenous levels of H(2… (More)

Although oxidatively damaged lipoproteins are implicated in vascular injury, there is little information regarding the role of… (More)

Free radicals or reactive oxygen species are thought to contribute to the pathology of many diseases. These include inflammatory… (More)

Thiol oxidation by hypochlorous acid and chloramines is a favorable reaction and may be responsible for alterations in regulatory… (More)

Myeloperoxidase uses hydrogen peroxide (H2O2) to generate hypochlorous acid (HOCl), a potent cytotoxic oxidant. We demonstrate… (More)

Hypochlorous acid (HOCl) is a potent oxidant, which is produced in vivo by activated phagocytes. This compound is an important… (More)

Disturbance of the balance between the production of reactive oxygen species such as superoxide; hydrogen peroxide; hypochlorous… (More)

Uric acid, or more correctly (at physiological pH values), its monoanion urate, is traditionally considered to be a metabolically… (More)

N-acetylcysteine has been widely used as an antioxidant in vivo and in vitro. Its reaction with four oxidant species has… (More)

The model hydrogen peroxide-myeloperoxidase-chloride system is capable of generating the powerful oxidant hypochlorous acid… (More)