Hydroxymethylglutaryl-CoA Synthase

Known as: HMG coA synthase, Hydroxymethylglutaryl CoA Synthase, HMG-CoA synthase 
An enzyme that catalyzes the synthesis of hydroxymethylglutaryl-CoA from acetyl-CoA and acetoacetyl-CoA. This is a key enzyme in steroid biosynthesis… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1972-2017
0102019722017

Papers overview

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Highly Cited
2009
Highly Cited
2009
BACKGROUND Artemisinin derivatives are the key active ingredients in Artemisinin combination therapies (ACTs), the most effective… (More)
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Highly Cited
2004
Highly Cited
2004
A screening program for bioactive compounds from marine cyanobacteria led to the isolation of jamaicamides A-C. Jamaicamide A is… (More)
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2004
2004
Curacin A (1) is a potent cancer cell toxin obtained from strains of the tropical marine cyanobacterium Lyngbya majuscula found… (More)
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Highly Cited
2001
Highly Cited
2001
We compared the ability of rat and human hepatocytes to respond to fenofibric acid and a novel potent phenylacetic acid… (More)
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Highly Cited
2000
Highly Cited
2000
The mevalonate pathway and the glyceraldehyde 3-phosphate (GAP)-pyruvate pathway are alternative routes for the biosynthesis of… (More)
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Highly Cited
1998
Highly Cited
1998
Membrane physiology, plasma lipid levels, and intracellular sterol homeostasis are regulated by both fatty acids and cholesterol… (More)
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1998
1998
3-Hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) synthase, a key regulatory enzyme in the pathway for endogenous cholesterol… (More)
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Highly Cited
1994
Highly Cited
1994
Fatty acids induce an increase in the transcription of the mitochondrial 3-hydroxy-3-methylglutaryl-CoA (HMG-CoA) synthase gene… (More)
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Highly Cited
1993
Highly Cited
1993
We report the cDNA cloning of SREBP-2, the second member of a family of basic-helix-loop-helix-leucine zipper (bHLH-Zip… (More)
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Highly Cited
1992
Highly Cited
1992
Cytosolic 3-hydroxy-3-methylglutaryl CoA (HMG-CoA) synthase (E.C. 4.1.3.5) is a highly regulated enzyme involved in isoprenoid… (More)
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