Activity and intracellular distribution of enzymes of ketone-body metabolism in rat liver.

@article{Williamson1968ActivityAI,
  title={Activity and intracellular distribution of enzymes of ketone-body metabolism in rat liver.},
  author={Dermot H. Williamson and M W Bates and Hans A. Krebs},
  journal={The Biochemical journal},
  year={1968},
  volume={108 3},
  pages={353-61}
}
1. The activities of hydroxymethylglutaryl-CoA synthase and lyase in rat liver were found to be two- to 15-fold greater than those reported by other authors under similar conditions. 2. When expressed on the basis of body weight, no appreciable differences were found between the activities of hydroxymethylglutaryl-CoA synthase in whole homogenates of livers from normal and starved rats. The synthase activity increased by 70% and 140% in livers of alloxan-diabetic rats and rats fed on a high-fat… CONTINUE READING
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