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Hydroxydopamine

 
National Institutes of Health

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DopamineHydroxydopamines

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2014
2014
Neuroprotective potentials of neurotrophin rich olfactory ensheathing cell's conditioned media against 6OHDA-induced oxidative damage.
On the basis of recent reports, we propose that impaired neurotrophin signaling (PI3k/Akt), low antioxidant levels, and… Expand
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2012
2012
Drinking hydrogen water and intermittent hydrogen gas exposure, but not lactulose or continuous hydrogen gas exposure, prevent 6-hydorxydopamine-induced Parkinson’s disease in rats
BackgroundLactulose is a synthetic disaccharide that can be catalyzed only by intestinal bacteria in humans and rodents, and a… Expand
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2010
2010
Bilateral six-hydroxydopamine administration to PFC prevents the expression of behavioral sensitization to methylphenidate
Psychostimulants like amphetamine and methylphenidate (MPD) are used to treat attention deficit hyperactivity disorder (ADHD… Expand
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2006
2006
Forebrain D1 function and sensorimotor gating in rats: Effects of D1 blockade, frontal lesions and dopamine denervation
Prefrontal D1 hypoactivity is implicated in the pathophysiology of schizophrenia, and might contribute to sensorimotor gating… Expand
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2004
2004
Studies of ATP sensitive potassium channels on 6 - hydroxydopamine and haloperidol rat models of Parkinson＇ s disease： Implications for treating Parkinson＇ s disease？
Parkinson' s disease is a common neurodegenerative movement disease that affects more than 1% of the elderly population… Expand
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1999
1999
Time-dependent striatal dopamine depletion after injection of 6-hydroxydopamine in the rat. Comparison of single bilateral and double bilateral lesions.
For future investigation of possible perturbation of circadian rhythm in animal models of Parkinson's disease we needed an animal… Expand
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1993
1993
Midbrain 6-hydroxydopamine lesions modulate blink reflex excitability
The blink reflex abnormalities present in the 6 hydroxydopamine (6-OHDA) lesioned rat model of parkinsonism mimicked those of the… Expand
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1991
1991
Long latency event-related potentials in rats: Effects of dopaminergic and serotonergic depletions
The effects of serotonergic and dopaminergic depletions on event-related potentials (ERPs) generated by an auditory "oddball… Expand
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1981
1981
Sympathetic innervation of murine thymus and spleen: Evidence for a functional link between the nervous and immune systems
Sympathetic innervation was demonstrated in both perivascular and parenchymal regions of murine thymus and spleen. Catecholamine… Expand
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1974
1974
Neonatal 6-hydroxydopamine sympathectomy in normotensive and spontaneously hypertensive rat.
Abstract Neonatal sympathectomy was produced in rats from either a normotensive or spontaneously hypertensive (SHR) strain by… Expand
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