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Hydroxychloroquine

Known as: Hydroxychlorochin, 2-((4-((7-chloro-4-Quinolyl)amino)pentyl)ethylamino)ethanol, 7-chloro-4-[5-(N-Ethyl-N-2-hydroxyethylamino)-2-pentyl]aminoquinoline 
A 4-aminoquinoline with immunosuppressive, antiautophagy, and antimalarial activities. Although the precise mechanism of action is unknown… 
National Institutes of Health

Related topics

Related topics

29 relations

Broader (3)

AntimalarialsChloroquineEnzyme Inhibitors
Antirheumatic AgentsDrug AllergyHydroxychloroquine SulfateHydroxychloroquine Sulfate 200 MG Oral Tablet
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Narrower (2)

Plaquenildesethylhydroxychloroquine

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2020
Highly Cited
2020
Observational Study of Hydroxychloroquine in Hospitalized Patients with Covid-19
Abstract Background Hydroxychloroquine has been widely administered to patients with Covid-19 without robust evidence supporting… 
Review
2020
Review
2020
Hydroxychloroquine and azithromycin as a treatment of COVID-19: results of an open-label non-randomized clinical trial
Highly Cited
2020
Highly Cited
2020
A Randomized Trial of Hydroxychloroquine as Postexposure Prophylaxis for Covid-19
Abstract Background Coronavirus disease 2019 (Covid-19) occurs after exposure to severe acute respiratory syndrome coronavirus 2… 
Review
2020
Review
2020
Mechanisms of action of hydroxychloroquine and chloroquine: implications for rheumatology
Despite widespread clinical use of antimalarial drugs such as hydroxychloroquine and chloroquine in the treatment of rheumatoid… 
Highly Cited
2020
Highly Cited
2020
Association of Treatment With Hydroxychloroquine or Azithromycin With In-Hospital Mortality in Patients With COVID-19 in New York State.
Importance Hydroxychloroquine, with or without azithromycin, has been considered as a possible therapeutic agent for patients… 
Highly Cited
2020
Highly Cited
2020
Hydroxychloroquine, a less toxic derivative of chloroquine, is effective in inhibiting SARS-CoV-2 infection in vitro
Dear Editor, The outbreak of coronavirus disease 2019 (COVID-19) caused by the severe acute respiratory syndrome coronavirus 2… 
Highly Cited
2020
Highly Cited
2020
Efficacy of hydroxychloroquine in patients with COVID-19: results of a randomized clinical trial
Aims: Studies have indicated that chloroquine (CQ) shows antagonism against COVID-19 in vitro. However, evidence regarding its… 
Highly Cited
2020
Highly Cited
2020
Hydroxychloroquine in patients with mainly mild to moderate coronavirus disease 2019: open label, randomised controlled trial
Abstract Objective To assess the efficacy and safety of hydroxychloroquine plus standard of care compared with standard of care… 
Highly Cited
2020
Highly Cited
2020
Hydroxychloroquine with or without Azithromycin in Mild-to-Moderate Covid-19
Abstract Background Hydroxychloroquine and azithromycin have been used to treat patients with coronavirus disease 2019 (Covid-19… 
Review
2006
Review
2006
Systemic lupus erythematosus
Systemic lupus erythematosus (SLE) is a clinically heterogeneous disease, which is autoimmune in origin and is characterized by… 
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