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desethylhydroxychloroquine

Known as: 2-((4-((7-Chloro-4-quinolyl)amino)pentyl)amino)ethanol, CLETOQUINE 
 
National Institutes of Health

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Related topics

3 relations

Broader (2)

HydroxychloroquineHydroxychloroquine Sulfate
analogs & derivatives

Papers overview

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2019
2019
Molecular docking studies of chloroquine and its derivatives against P23pro‐zbd domain of chikungunya virus: Implication in designing of novel therapeutic strategies
The arthropod‐transmitted chikungunya virus has emerged as an epidemic menace that causes debilitating polyarthritis. With this… Expand
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2017
2017
Factors Related to Blood Hydroxychloroquine Concentration in Patients With Systemic Lupus Erythematosus
To identify factors associated with blood concentrations of hydroxychloroquine (HCQ) and its major metabolite, N… Expand
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2017
2017
Capillary blood collected on volumetric absorptive microsampling (VAMS) device for monitoring hydroxychloroquine in rheumatoid arthritis patients
&NA; A novel technique for collection of capillary blood, termed volumetric absorptive microsampling (VAMS), has been recently… Expand
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2015
2015
Development and validation of a clinical HPLC method for the quantification of hydroxychloroquine and its metabolites in whole blood
Background: Therapeutic drug monitoring for hydroxychloroquine (HCQ) has been suggested to assess nonadherence and optimize… Expand
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Highly Cited
2002
Highly Cited
2002
Hydroxychloroquine concentration-response relationships in patients with rheumatoid arthritis.
OBJECTIVE A dose-response relationship for hydroxychloroquine (HCQ), in terms of the proportion of patients achieving the Paulus… Expand
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1993
1993
Determination of the stereoisomers of hydroxychloroquine and its major metabolites in plasma and urine following a single oral administration of racemic hydroxychloroquine.
Plaquenil (hydroxychloroquine, HCQ; Sanofi Winthrop Pharmaceuticals, New York, NY) is a stereoisomeric drug administered as a… Expand
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1993
1993
Enantioselective determination of hydroxychloroquine and its major metabolites in urine and the observation of a reversal in the (+)/(-)-hydroxychloroquine ratio.
A sequential achiral-chiral high-performance liquid chromatographic system has been developed for the quantitation in urine of… Expand
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1992
1992
Determination of hydroxychloroquine and its major metabolites in plasma using sequential achiral-chiral high-performance liquid chromatography.
A sequential achiral-chiral high-performance liquid chromatographic system has been developed for the determination of the… Expand
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1985
1985
High-performance liquid chromatographic assay for hydroxychloroquine and metabolites in blood and plasma, using a stationary phase of poly(styrene divinylbenzene) and a mobile phase at pH 11, with…
A sensitive rapid high-performance liquid chromatographic assay for hydroxychloroquine and three major metabolites… Expand
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1966
1966
Studies of the metabolism of some compounds of the 4-amino-7-chloroquinoline series.
Methods for the determination of hydroxychloroquine, desethylchloroquine (SN-13616), bisdesethylchloroquine (SN-13617… Expand
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