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Hycamtin

 
National Institutes of Health

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2010
2010
Topotecan (TPT) is in clinical use as an antitumor agent, hycamtin. Because of this, it requires both biologically and chemically… Expand
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2006
2006
The objective of this study was to study the efficacy and adverse effects of hycamtin for small-cell lung cancer treatment… Expand
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2003
2003
  • Y. Zhang, X. Zhi, +7 authors S. Yang
  • Zhonghua zhong liu za zhi [Chinese journal of…
  • 2003
  • Corpus ID: 7159080
OBJECTIVE To discuss the therapeutic effect and toxicity of second line Hycamtin for lung cancer patients. METHODS Ten of these… Expand
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2002
2002
Objective To examine the effect of Hycamtin on two kinds of endometrial carcinoma cell lines, Ishikawa 3H12 and HEC 1A. Methods… Expand
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2001
2001
Abstract. O'Toole SA, Sheppard BL, McGuinness E, Gleeson NC, Bonnar J. Serous papillary adenocarcinomas of the ovary display… Expand
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2001
2001
BACKGROUND Since no effective therapeutic approach is yet known for metastatic renal cell carcinoma (RCC), we analyzed the… Expand
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Highly Cited
1999
Highly Cited
1999
Prolonged exposure to topotecan in in vitro and in vivo experiments has yielded the highest antitumor efficacy. An oral… Expand
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Highly Cited
1998
Highly Cited
1998
Purpose: We have previously reported that DX-8951f, a water-soluble and nonprodrug camptothecin (CPT) derivative, exhibits both… Expand
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1998
1998
Hycamtin is a camptothecin anticancer analogue containing a dimethylaminomethyl substituent at position 9 and a hydroxy… Expand
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1997
1997
Publisher Summary There was a slight increase in the number of new chemical entities (NCEs) introduced in the world market in the… Expand
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