Histopathologic Grade differentiation

Known as: Cellular Differentiation, Differentiation 
In cancer, refers to how mature (developed) the cancer cells are in a tumor. Differentiated tumor cells resemble normal cells and tend to grow and… (More)
National Institutes of Health

Papers overview

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Review
2017
Review
2017
The SH-SY5Y cell line in Parkinson’s disease research: a systematic review
Parkinson’s disease (PD) is a devastating and highly prevalent neurodegenerative disease for which only symptomatic treatment is… (More)
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Review
2012
Review
2012
Metabolic reprogramming: a cancer hallmark even warburg did not anticipate.
Cancer metabolism has long been equated with aerobic glycolysis, seen by early biochemists as primitive and inefficient. Despite… (More)
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Highly Cited
2008
Highly Cited
2008
Genome-scale DNA methylation maps of pluripotent and differentiated cells
DNA methylation is essential for normal development and has been implicated in many pathologies including cancer. Our knowledge… (More)
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Highly Cited
2008
Highly Cited
2008
Connecting microRNA Genes to the Core Transcriptional Regulatory Circuitry of Embryonic Stem Cells
MicroRNAs (miRNAs) are crucial for normal embryonic stem (ES) cell self-renewal and cellular differentiation, but how miRNA gene… (More)
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Highly Cited
2005
Highly Cited
2005
c-Myc-regulated microRNAs modulate E2F1 expression
MicroRNAs (miRNAs) are 21–23 nucleotide RNA molecules that regulate the stability or translational efficiency of target messenger… (More)
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Review
2005
Review
2005
Stochasticity in gene expression: from theories to phenotypes
Genetically identical cells exposed to the same environmental conditions can show significant variation in molecular content and… (More)
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Highly Cited
2002
Highly Cited
2002
Prediction of Plant MicroRNA Targets
We predict regulatory targets for 14 Arabidopsis microRNAs (miRNAs) by identifying mRNAs with near complementarity. Complementary… (More)
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Highly Cited
2002
Highly Cited
2002
Memory CD8+ T cells vary in differentiation phenotype in different persistent virus infections
The viruses HIV-1, Epstein–Barr virus (EBV), cytomegalovirus (CMV) and hepatitis C virus (HCV) are characterized by the… (More)
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Review
2001
Review
2001
Chromosome territories, nuclear architecture and gene regulation in mammalian cells
The expression of genes is regulated at many levels. Perhaps the area in which least is known is how nuclear organization… (More)
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Highly Cited
1969
Highly Cited
1969
Positional information and the spatial pattern of cellular differentiation.
The problem of pattern is considered in terms of how genetic information can be translated in a reliable manner to give specific… (More)
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