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High Affinity Immunoglobulin Gamma Fc Receptor I, human

Known as: Fc Gamma Receptor, IgG Fc Receptor I, CD64 Antigen 
High affinity immunoglobulin gamma Fc receptor I (374 aa, ~43 kDa) is encoded by the human FCGR1A gene. This protein is involved in the immune… 
National Institutes of Health

Related topics

Related topics

12 relations
Antigen PresentationAntigen ProcessingFCGR1A geneImmunoglobulin C2-set Domain

Broader (1)

CD64 Antigen

Papers overview

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2007
2007
Monocyte cholesterol homeostasis correlates with the presence of detergent resistant membrane microdomains
Lipid membrane microdomains are involved in the regulation of biological functions of monocyte membrane proteins. These… 
Highly Cited
2004
Highly Cited
2004
Direct interaction between FcgammaRI (CD64) and periplakin controls receptor endocytosis and ligand binding capacity.
FcgammaRI depends for its biological function on both the intracellular domain of the alpha-chain and associated Fc receptor (FcR… 
2004
2004
Efficient eukaryotic expression of fluorescent scFv fusion proteins directed against CD antigens for FACS applications.
Review
2002
Review
2002
Bispecific antibodies targeting cancer cells.
In recent years, antibody therapy has become a new treatment modality for tumour patients, although the majority of responses are… 
Highly Cited
2001
Highly Cited
2001
Exogenous antigen targeted to FcgammaRI on myeloid cells is presented in association with MHC class I.
1999
1999
Activation of three classes of nonreceptor tyrosine kinases following Fc gamma receptor crosslinking in human monocytes.
Fc gamma receptors on monocytes/macrophages play an important role in both host defense and autoimmune disorders. Fc gamma… 
1998
1998
High Affinity Receptor for IgG (FcγRI/CD64) Gene and STAT Protein Binding to the IFN-γ Response Region (GRR) Are Regulated Differentially in Human Neutrophils and Monocytes by IL-10
Since IL-10 has been shown to up-regulate the expression of the high affinity receptor for IgG (FcγRI/CD64) in human monocytes… 
1998
1998
High affinity receptor for IgG (Fc gamma RI/CD64) gene and STAT protein binding to the IFN-gamma response region (GRR) are regulated differentially in human neutrophils and monocytes by IL-10.
Since IL-10 has been shown to up-regulate the expression of the high affinity receptor for IgG (FcgammaRI/CD64) in human… 
Highly Cited
1995
Highly Cited
1995
Mature polymorphonuclear leukocytes express high‐affinity receptors for IgG (FcγRI) after stimulation with granulocyte colony‐stimulating factor (G‐CSF)
The high‐affinity receptor for the constant region of immunoglobulin G IgG (FcγRI; CD64) is virtually undetectable on mature… 
1991
1991
Gene organization of the human high affinity receptor for IgG, Fc gamma RI (CD64). Characterization and evidence for a second gene.
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