High Affinity Immunoglobulin Gamma Fc Receptor I, human

Known as: Fc Gamma Receptor, IgG Fc Receptor I, CD64 Antigen 
High affinity immunoglobulin gamma Fc receptor I (374 aa, ~43 kDa) is encoded by the human FCGR1A gene. This protein is involved in the immune… (More)
National Institutes of Health

Related topics

Related topics

12 relations
Antigen PresentationAntigen ProcessingFCGR1A geneImmunoglobulin C2-set Domain
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Broader (1)

CD64 Antigen

Papers overview

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Highly Cited
2012
Highly Cited
2012
CD64 expression distinguishes monocyte-derived and conventional dendritic cells and reveals their distinct role during intramuscular immunization.
Although most vaccines are administered i.m., little is known about the dendritic cells (DCs) that are present within skeletal… (More)
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Highly Cited
2009
Highly Cited
2009
Macrophages in vaginal but not intestinal mucosa are monocyte-like and permissive to human immunodeficiency virus type 1 infection.
Mucosal surfaces play a major role in human immunodeficiency virus type 1 (HIV-1) transmission and pathogenesis, and yet the role… (More)
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Highly Cited
2006
Highly Cited
2006
Differential enhancement of dengue virus immune complex infectivity mediated by signaling-competent and signaling-incompetent human Fcgamma RIA (CD64) or FcgammaRIIA (CD32).
Fcgamma receptor (FcgammaR)-mediated entry of infectious dengue virus immune complexes into monocytes/macrophages is hypothesized… (More)
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Highly Cited
2004
Highly Cited
2004
Inducible nitric oxide synthase in chronic active multiple sclerosis plaques: distribution, cellular expression and association with myelin damage
Inducible nitric oxide synthase (iNOS) is an enzyme that produces nitric oxide (NO) and is thought to contribute to the… (More)
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2001
2001
A comparison of mediators released or generated by IFN-gamma-treated human mast cells following aggregation of Fc gamma RI or Fc epsilon RI.
The high affinity receptor for IgG (Fc gamma RI, CD64) is expressed on human mast cells, where it is up-regulated by IFN-gamma… (More)
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2001
2001
Increased distribution and expression of CD64 on blood polymorphonuclear cells from patients with the systemic inflammatory response syndrome (SIRS).
Evidence is growing to suggest that the multiple organ damage of the systemic inflammatory response syndrome (SIRS) arises from… (More)
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Highly Cited
1999
Highly Cited
1999
The Major Receptor for C-Reactive Protein on Leukocytes Is Fcγ Receptor II
C-reactive protein (CRP) is an acute phase serum protein that shares several functions with immunoglobulin (Ig)G including… (More)
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Highly Cited
1998
Highly Cited
1998
Phagocytosis of the malarial pigment, hemozoin, impairs expression of major histocompatibility complex class II antigen, CD54, and CD11c in human monocytes.
In Plasmodium falciparum malaria, large proportions of resident macrophages and circulating monocytes and leukocytes contain… (More)
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Highly Cited
1996
Highly Cited
1996
Antigen targeting to myeloid-specific human Fc gamma RI/CD64 triggers enhanced antibody responses in transgenic mice.
Besides their phagocytic effector functions, myeloid cells have an essential role as accessory cells in the induction of optimal… (More)
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Highly Cited
1991
Highly Cited
1991
Neutrophils express the high affinity receptor for IgG (Fc gamma RI, CD64) after in vivo application of recombinant human granulocyte colony-stimulating factor.
Fc receptors are important effector molecules of neutrophilic granulocytes (polymorphonuclear neutrophils [PMN]), connecting… (More)
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