Heterozygote

Known as: heterozygous genotype, Heterozygous, Heterozygosity 
Occurs when the two alleles at a particular gene locus are different. A heterozygous genotype may include one normal allele and one mutation, or two… (More)
National Institutes of Health

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Highly Cited
2005
Highly Cited
2005
BACKGROUND Polycythemia vera, essential thrombocythemia, and idiopathic myelofibrosis are clonal myeloproliferative disorders… (More)
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Highly Cited
2004
Highly Cited
2004
A large number of tiny noncoding RNAs have been cloned and named microRNAs (miRs). Recently, we have reported that miR-15a and… (More)
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Highly Cited
2004
Highly Cited
2004
The population genetic pattern known as "isolation by distance" results from spatially limited gene flow and is a commonly… (More)
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Highly Cited
2004
Highly Cited
2004
We conducted a population-based study on glioblastomas in the Canton of Zurich, Switzerland (population, 1.16 million) to… (More)
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Highly Cited
2000
Highly Cited
2000
Chk1, an evolutionarily conserved protein kinase, has been implicated in cell cycle checkpoint control in lower eukaryotes. By… (More)
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Highly Cited
1995
Highly Cited
1995
Currently used tests of Hardy-Weinberg proportions do not take into account the nature of the alternative hypothesis, which is… (More)
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Highly Cited
1995
Highly Cited
1995
Loss of heterozygosity on chromosome 9p21 is one of the most frequent genetic alterations identified in human cancer. The rate of… (More)
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Highly Cited
1983
Highly Cited
1983
With the aim of analyzing and interpreting data on DNA polymorphism obtained by DNA sequencing or restriction enzyme technique, a… (More)
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Highly Cited
1978
Highly Cited
1978
The magnitudes of the systematic biases involved in sample heterozygosity and sample genetic distances are evaluated, and… (More)
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Highly Cited
1973
Highly Cited
1973
  • Masatoshi Nei
  • Proceedings of the National Academy of Sciences…
  • 1973
A method is presented by which the gene diversity (heterozygosity) of a subdivided population can be analyzed into its components… (More)
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