• Publications
  • Influence
Effects of dietary omega-3 polyunsaturated fatty acids on brain gene expression.
It is concluded that PUFA-enriched diets lead to significant changes in expression of several genes in the central nervous tissue, and these effects appear to be mainly independent of their effects on membrane composition.
Oleic acid content is responsible for the reduction in blood pressure induced by olive oil
It is demonstrated that olive oil induces its hypotensive effects through the action of OA, and the OA analogues, elaidic and stearic acids, had no hypotensive activity, indicating that the molecular mechanisms that link membrane lipid structure and BP regulation are very specific.
Sphingomyelin and sphingomyelin synthase (SMS) in the malignant transformation of glioma cells and in 2-hydroxyoleic acid therapy
It is proposed that the regulation of SMS activity in tumor cells is a critical upstream event in 2OHOA antitumor mechanism, which also explains its specificity for cancer cells, its potency, and the lack of undesired side effects.
Multiple forms of supernatant malate dehydrogenase in salmonid fishes.
Two rounds of gene duplication for supernatant malate dehydrogenase have taken place before or during the evolution of salmonid fishes, suggesting that the A and B subunits are the products of duplicate genes which have undergone limited evolutionary divergence.
Ascorbic Acid Requirements of Coho Salmon and Rainbow Trout
Wound repair was delayed or inhibited in fish on low C diets and results generally supported diet and tissue levels needed for rapid growth and absence of histopathology.