Heterozygote Detection

Among the human health conditions linked to microbial communities, phenotypes are often associated with only a subset of strains… (More)

Pancreatic ductal adenocarcinoma (PDA) has a dismal prognosis and insights into both disease etiology and targeted intervention… (More)

MOTIVATION The ability to detect copy-number variation (CNV) and loss of heterozygosity (LOH) from exome sequencing data extends… (More)

The eubacterial genus Wolbachia comprises one of the most abundant groups of obligate intracellular bacteria, and it has a host… (More)

Interpretation of genetic differentiation values is often problematic because of their dependence on the level of genetic… (More)

The statistical power of five association study test statistics (two haplotype-based tests, two marker-based tests, and the… (More)

BACKGROUND Usual ductal hyperplasia (UDH), atypical ductal hyperplasia (ADH), and ductal carcinoma in situ (DCIS) are risk… (More)

BACKGROUND Published heritability estimates (h2) for body mass index (BMI) range from as low as 0.05 to as high as 0.90. The… (More)

The structural gene locus for apolipoprotein E (apo E) is polymorphic. Three common alleles (epsilon 2, epsilon 3, epsilon 4… (More)

The clinical, radiological, and pathological findings in three siblings affected with the autosomal recessive syndrome of… (More)