Hepatocyte Nuclear Factor 3-alpha

Known as: Forkhead Box Protein A1, HNF-3A Transcription Factor, TCF-3A 
Hepatocyte nuclear factor 3-alpha (472 aa, ~49 kDa) is encoded by the human FOXA1 gene. This protein plays a role in the modulation of transcription.
National Institutes of Health

Papers overview

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Highly Cited
2015
Highly Cited
2015
Invasive lobular carcinoma (ILC) is the second most prevalent histologic subtype of invasive breast cancer. Here, we… (More)
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Highly Cited
2012
Highly Cited
2012
Characterization of the prostate cancer transcriptome and genome has identified chromosomal rearrangements and copy number gains… (More)
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Highly Cited
2012
Highly Cited
2012
Oestrogen receptor-α (ER) is the defining and driving transcription factor in the majority of breast cancers and its target genes… (More)
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Highly Cited
2012
Highly Cited
2012
Prostate cancer is the second most common cancer in men worldwide and causes over 250,000 deaths each year. Overtreatment of… (More)
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Highly Cited
2011
Highly Cited
2011
The location and timing of cellular differentiation must be stringently controlled for proper organ formation. Normally… (More)
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Highly Cited
2010
Highly Cited
2010
Chromatin plays a central role in eukaryotic gene regulation. We performed genome-wide mapping of epigenetically marked… (More)
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Highly Cited
2009
Highly Cited
2009
The evolution of prostate cancer from an androgen-dependent state to one that is androgen-independent marks its lethal… (More)
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Highly Cited
2009
Highly Cited
2009
We used ChIP-Seq to map ERalpha-binding sites and to profile changes in RNA polymerase II (RNAPII) occupancy in MCF-7 cells in… (More)
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Highly Cited
2005
Highly Cited
2005
The specification of the vertebrate liver is thought to occur in a two-step process, beginning with the establishment of… (More)
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1995
1995
Three distinct hepatocyte nuclear factor 3 (HNF-3) proteins (alpha, beta, and gamma) are known to regulate the transcription of… (More)
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