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Hemoglobin Subunit Alpha
Known as:
Alpha Globin
, Alpha-Globin
, Hemoglobin Alpha Chain
Hemoglobin subunit alpha (142 aa, ~15 kDa) is encoded by both the human HBA1 and human HBA2 genes. This protein plays a role in the distribution of…
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National Institutes of Health
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Related topics
Related topics
10 relations
Cellular Membrane
Erythrocytes
HBA1 gene
HBA2 gene
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Review
2000
Review
2000
Sickle hemoglobin (HbS) allele and sickle cell disease: a HuGE review.
A. Ashley-Koch
,
Quanhe Yang
,
R. Olney
American Journal of Epidemiology
2000
Corpus ID: 7487450
Sickle cell disease is caused by a variant of the beta-globin gene called sickle hemoglobin (Hb S). Inherited autosomal…
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Highly Cited
1995
Highly Cited
1995
Mutations in a putative global transcriptional regulator cause X-linked mental retardation with α-thalassemia (ATR-X syndrome)
R. Gibbons
,
D. Picketts
,
L. Villard
,
D. Higgs
Cell
1995
Corpus ID: 16411046
Highly Cited
1990
Highly Cited
1990
The expected equilibrium of the CpG dinucleotide in vertebrate genomes under a mutation model.
J. Sved
,
Adrian BIRDt
Proceedings of the National Academy of Sciences…
1990
Corpus ID: 36292539
The CpG dinucleotide is present at approximately 20% of its expected frequency in vertebrate genomes, a deficiency thought due to…
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Review
1989
Review
1989
A review of the molecular genetics of the human alpha-globin gene cluster.
D. Higgs
,
M. Vickers
,
A. Wilkie
,
I. Pretorius
,
A. Jarman
,
D. Weatherall
Blood
1989
Corpus ID: 45009157
Highly Cited
1988
Highly Cited
1988
Human CCAAT-binding proteins have heterologous subunits
L. Chodosh
,
A. Baldwin
,
R. Carthew
,
P. Sharp
Cell
1988
Corpus ID: 40338329
Highly Cited
1988
Highly Cited
1988
Role of RNase H in hybrid-arrested translation by antisense oligonucleotides.
R. Walder
,
J. A. Walder
Proceedings of the National Academy of Sciences…
1988
Corpus ID: 25758674
The mechanism of hybrid-arrested translation by antisense oligodeoxynucleotides has been investigated with the rabbit…
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Highly Cited
1987
Highly Cited
1987
A cellular DNA-binding protein that activates eukaryotic transcription and DNA replication
K. Jones
,
J. T. Kadonaga
,
P. Rosenfeld
,
T. Kelly
,
R. Tjian
Cell
1987
Corpus ID: 35196849
Highly Cited
1983
Highly Cited
1983
A cDNA cloning vector that permits expression of cDNA inserts in mammalian cells.
H. Okayama
,
P. Berg
Molecular and Cellular Biology
1983
Corpus ID: 21512711
This paper describes a plasmid vector for cloning cDNAs in Escherichia coli; the same vector also promotes expression of the cDNA…
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Highly Cited
1982
Highly Cited
1982
The interaction of alpha-thalassemia and homozygous sickle-cell disease.
D. Higgs
,
B. Aldridge
,
+8 authors
G. Serjeant
New England Journal of Medicine
1982
Corpus ID: 19435536
Patients with homozygous sickle-cell disease may be homozygous for alpha-thalassemia 2 (alpha-/alpha-), may be heterozygous for…
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Highly Cited
1981
Highly Cited
1981
Identification of DNA sequences required for transcription of the human α1-globin gene in a new SV40 host-vector system
P. Mellon
,
V. Parker
,
Y. Gluzman
,
T. Maniatis
Cell
1981
Corpus ID: 19629743
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