Hemoglobin Subunit Alpha

Known as: Alpha Globin, Alpha-Globin, Hemoglobin Alpha Chain 
Hemoglobin subunit alpha (142 aa, ~15 kDa) is encoded by both the human HBA1 and human HBA2 genes. This protein plays a role in the distribution of… (More)
National Institutes of Health

Papers overview

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Highly Cited
2009
Highly Cited
2009
Adaptive modifications of heteromeric proteins may involve genetically based changes in single subunit polypeptides or parallel… (More)
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Highly Cited
2008
Highly Cited
2008
Genes on different chromosomes can be spatially associated in the nucleus in several transcriptional and regulatory situations… (More)
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Highly Cited
2006
Highly Cited
2006
We describe a pathogenetic mechanism underlying a variant form of the inherited blood disorder alpha thalassemia. Association… (More)
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Highly Cited
2000
Highly Cited
2000
The stable introduction of a functional beta-globin gene in haematopoietic stem cells could be a powerful approach to treat beta… (More)
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Highly Cited
2000
Highly Cited
2000
We describe a sensitive, reliable and reproducible method, based on three multiplex PCR assays, for the rapid detection of seven… (More)
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Highly Cited
1999
Highly Cited
1999
The stable globin mRNAs provide an ideal system for studying the mechanism governing mammalian mRNA turnover. alpha-Globin mRNA… (More)
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Highly Cited
1997
Highly Cited
1997
Splicing of small introns in lower eucaryotes can be distinguished from vertebrate splicing by the inability of such introns to… (More)
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Highly Cited
1995
Highly Cited
1995
The ATR-X syndrome is an X-linked disorder comprising severe psychomotor retardation, characteristic facial features, genital… (More)
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Highly Cited
1990
Highly Cited
1990
The CpG dinucleotide is present at approximately 20% of its expected frequency in vertebrate genomes, a deficiency thought due to… (More)
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Highly Cited
1983
Highly Cited
1983
This paper describes a plasmid vector for cloning cDNAs in Escherichia coli; the same vector also promotes expression of the cDNA… (More)
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