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Hemoglobin Subunit Alpha

Known as: Alpha Globin, Alpha-Globin, Hemoglobin Alpha Chain 
Hemoglobin subunit alpha (142 aa, ~15 kDa) is encoded by both the human HBA1 and human HBA2 genes. This protein plays a role in the distribution of… Expand
National Institutes of Health

Related topics

Related topics

10 relations
Cellular MembraneErythrocytesHBA1 geneHBA2 gene
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Papers overview

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Highly Cited
2000
Highly Cited
2000
Rapid detection of α‐thalassaemia deletions and α‐globin gene triplication by multiplex polymerase chain reactions
We describe a sensitive, reliable and reproducible method, based on three multiplex PCR assays, for the rapid detection of seven… Expand
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Highly Cited
1995
Highly Cited
1995
Mutations in a putative global transcriptional regulator cause X-linked mental retardation with α-thalassemia (ATR-X syndrome)
The ATR-X syndrome is an X-linked disorder comprising severe psychomotor retardation, characteristic facial features, genital… Expand
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Highly Cited
1990
Highly Cited
1990
Localization of specific mRNAs in Xenopus embryos by whole-mount in situ hybridization.
We have adapted a non-radioactive technique to detect localized mRNAs in whole-mount Xenopus embryos. Synthetic antisense RNA… Expand
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Highly Cited
1990
Highly Cited
1990
The expected equilibrium of the CpG dinucleotide in vertebrate genomes under a mutation model.
  • J. Sved, A. Bird
  • Proceedings of the National Academy of Sciences…
  • 1990
    • Corpus ID: 36292539
The CpG dinucleotide is present at approximately 20% of its expected frequency in vertebrate genomes, a deficiency thought due to… Expand
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Highly Cited
1988
Highly Cited
1988
Human CCAAT-binding proteins have heterologous subunits
We have characterized three distinct proteins present in HeLa cell extracts that specifically recognize different subsets of… Expand
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Highly Cited
1988
Highly Cited
1988
Role of RNase H in hybrid-arrested translation by antisense oligonucleotides.
  • R. Walder, J. Walder
  • Proceedings of the National Academy of Sciences…
  • 1988
    • Corpus ID: 25758674
The mechanism of hybrid-arrested translation by antisense oligodeoxynucleotides has been investigated with the rabbit… Expand
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Highly Cited
1987
Highly Cited
1987
A cellular DNA-binding protein that activates eukaryotic transcription and DNA replication
Transcription factor CTF, which is responsible for selective recognition of eukaryotic promoters that contain the sequence CCAAT… Expand
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Highly Cited
1983
Highly Cited
1983
A cDNA cloning vector that permits expression of cDNA inserts in mammalian cells.
This paper describes a plasmid vector for cloning cDNAs in Escherichia coli; the same vector also promotes expression of the cDNA… Expand
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Highly Cited
1982
Highly Cited
1982
The interaction of alpha-thalassemia and homozygous sickle-cell disease.
Patients with homozygous sickle-cell disease may be homozygous for alpha-thalassemia 2 (alpha-/alpha-), may be heterozygous for… Expand
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Highly Cited
1981
Highly Cited
1981
Identification of DNA sequences required for transcription of the human α1-globin gene in a new SV40 host-vector system
We have developed a rapid and simple method for studying the transcription of cloned eucaryotic genes, which involves… Expand
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