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Heat Shock 70 kDa Protein 1A/1B

Known as: HSP72, Heat Shock 70 kDa Protein 1/2, HSP70.1/HSP70.2 
Heat shock 70 kDa protein 1A/1B (641 aa, ~70 kDa) is encoded by the human HSPA1A and HSPA1B genes. This protein is involved in the mediation of… 
National Institutes of Health

Related topics

Related topics

17 relations
Cell Growth RegulationCytoplasmEndoplasmic ReticulumHSPA1A gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2012
2012
Hyperthermia With Mild Electrical Stimulation Protects Pancreatic β-Cells From Cell Stresses and Apoptosis
Induction of heat shock protein (HSP) 72 improves metabolic profiles in diabetic model mice. However, its effect on pancreatic… 
Review
2010
Review
2010
Dual Role of Heat Shock Proteins as Regulators of Apoptosis and Innate Immunity
Stress or heat shock proteins (HSPs) 70 and 90 are powerful chaperones whose expression is induced in response to a wide variety… 
Highly Cited
2003
Highly Cited
2003
Role of extracellular HSP72 in acute stress-induced potentiation of innate immunity in active rats.
Acute stress can compromise acquired, and potentiate innate, immunity. Recent evidence suggests that the impact of stress on… 
Highly Cited
2002
Highly Cited
2002
Hsp72 and Stress Kinase c-jun N-Terminal Kinase Regulate the Bid-Dependent Pathway in Tumor Necrosis Factor-Induced Apoptosis
ABSTRACT The major inducible heat shock protein Hsp72 has been shown to protect cells from certain apoptotic stimuli. Here we… 
Highly Cited
2002
Highly Cited
2002
Gene transfer of HSP72 protects cornu ammonis 1 region of the hippocampus neurons from global ischemia: Influence of Bcl‐2
We investigated whether HSV gene transfer of HSP72 in vivo and in vitro: (1) protected cornu ammonis 1 region of the hippocampus… 
Highly Cited
2000
Highly Cited
2000
HSP72 as a complementary protection against oxidative stress induced by exercise in the soleus muscle of rats.
Given the potential of reactive oxygen species to damage intracellular proteins during subsequent bouts of muscle contractions… 
Highly Cited
1999
Highly Cited
1999
Post‐transcriptional regulation of the Bacillus subtilis dnaK operon
The heptacistronic dnaK heat shock operon of Bacillus subtilis consists of the genes hrcA, grpE, dnaK, dnaJ, orf35, orf28 and… 
Highly Cited
1995
Highly Cited
1995
A stress‐inducible 72‐kDa heat‐shock protein (HSP72) is expressed on the surface of human tumor cells, but not on normal cells
It is suggested that members of the heat‐shock protein (HSP) 70 and 90 families are involved in intracellular antigen processing… 
Highly Cited
1992
Highly Cited
1992
Heat Shock Protein Induction in Rat Hearts: A Role for Improved Myocardial Salvage After Ischemia and Reperfusion?
BackgroundTo test the hypothesis that the heat shock response is associated with improved myocardial salvage after myocardial… 
Highly Cited
1990
Highly Cited
1990
Hypoxia-ischemia induces heat shock protein-like (HSP72) immunoreactivity in neonatal rat brain.
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