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Haloperidol

Known as: Haloperidol [Chemical/Ingredient], 1-(3-P-Fluorobenzoylpropyl)-4-P-chlorophenyl-4-hydroxypiperidine, 4'-Fluoro-4-(4-hydroxy-4-(4'-chlorophenyl)piperidino)butyrophenone 
A phenylbutylpiperadine derivative with antipsychotic, neuroleptic, and antiemetic activities. Haloperidol competitively blocks postsynaptic dopamine… 
National Institutes of Health

Related topics

Related topics

40 relations
1 ML haloperidol decanoate 100 MG/ML Injection1 ML haloperidol decanoate 50 MG/ML Injection [Haldol]Bone Marrow DiseasesCYP1A2 protein, human

Broader (7)

AntiemeticsAntipsychotic AgentsButyrophenonesDopamine Antagonists

Narrower (8)

HaldolR-1625bromperidolbromperidol decanoate

Papers overview

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Highly Cited
1984
Highly Cited
1984
Haloperidol. Plasma levels and prolactin response as predictors of clinical improvement in schizophrenia: chemical v radioreceptor plasma level assays.
The relationship between clinical response of schizophrenic patients to haloperidol and (1) blood levels of the medication… 
1983
1983
Effect of haloperidol, suckling, oxytocin and hand milking on plasma relaxin and prolactin concentrations in cyclic and lactating pigs.
Prolactin secretion was stimulated in 5 cyclic gilts during the luteal phase (Day 10-13) with 5 mg haloperidol given i.v… 
Highly Cited
1981
Highly Cited
1981
Adrenergic and dopaminergic modulation of growth hormone and prolactin secretion in normal and tumor bearing human pituitaries in monolayer culture.
Adrenergic and dopaminergic agonists administered in vivo stimulate GH secretion and inhibit PRL release. To investigate the… 
1980
1980
Anomalous behavioral response to imidazoleacetic acid, a GABA agonist, in animals treated chronically with haloperidol.
Short-term haloperidol treatment decreases the stimulant effects of drugs with dopaminelike actions, while withdrawal from long… 
1978
1978
Effect of haloperidol and apomorphine treatment on dopamine receptors in pituitary and striatum.
Prompted by an interest in the similarity of brain and tuberoinfundibular systems, the authors studied butaclamol-specific… 
1978
1978
Effect of haloperidol and L-dopa on plasma prolactin in stalk-sectioned and intact monkeys.
To investigate further possible direct effects of dopamine agonists and antagonists upon the lactotropic cell in vivo, the PRL… 
Highly Cited
1976
Highly Cited
1976
Effects of fentanyl and droperidol on the dopamine metabolism of the rat striatum.
Fentanyl in low doses (0.02-0.05 mg/kg) had no significant effect on the dopamine turnover 20 min after intraperitoneal (i.p… 
Highly Cited
1975
Highly Cited
1975
Dopamine Induced Relaxation of Isolated Canine Renal, Mesenteric, and Femoral Arteries Contracted with Prostaglandin F2α
The purpose of this investigation was to develop a system for studying the effects of dopamine on isolated blood vessels. Canine… 
Highly Cited
1973
Highly Cited
1973
REVERSAL OF SOME THERAPEUTIC EFFECTS OF AN ANTIPSYCHOTIC AGENT BY AN ANTIPARKINSONISM DRUG
Data are presented from a multidimensional, longitudinal study in 10 acute schizophrenics which indicate that the addition of… 
1968
1968
Haloperidol in emotionally disturbed mentally retarded individuals.
The authors report a clinical study of the efficacy of a butyrophenone derivative (haloperidol) in a sample of mentally retarded…