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Haloperidol

Known as: Haloperidol [Chemical/Ingredient], 1-(3-P-Fluorobenzoylpropyl)-4-P-chlorophenyl-4-hydroxypiperidine, 4'-Fluoro-4-(4-hydroxy-4-(4'-chlorophenyl)piperidino)butyrophenone 
A phenylbutylpiperadine derivative with antipsychotic, neuroleptic, and antiemetic activities. Haloperidol competitively blocks postsynaptic dopamine… Expand
National Institutes of Health

Papers overview

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Review
2008
Review
2008
Guideline developers use a bewildering variety of systems to rate the quality of the evidence underlying their recommendations… Expand
Highly Cited
2005
Highly Cited
2005
Objectives: To study the effectiveness of haloperidol prophylaxis on incidence, severity, and duration of postoperative delirium… Expand
Highly Cited
2002
Highly Cited
2002
BACKGROUND Prevention of relapse is a major goal of maintenance treatment in patients with psychotic disorders. We performed a… Expand
Highly Cited
2002
Highly Cited
2002
OBJECTIVE Newer antipsychotic drugs have shown promise in ameliorating neurocognitive deficits in patients with schizophrenia… Expand
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Highly Cited
1999
Highly Cited
1999
Objective: To compare effects of risperidone with placebo (efficacy and tolerability) and haloperidol (tolerability) for treating… Expand
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Highly Cited
1997
Highly Cited
1997
Five fixed doses of the atypical antipsychotic "Seroquel" (quetiapine) were evaluated to delineate a dose-response relationship… Expand
Highly Cited
1988
Highly Cited
1988
The effect of various drugs on the extracellular concentration of dopamine in two terminal dopaminergic areas, the nucleus… Expand
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Highly Cited
1988
Highly Cited
1988
The treatment of schizophrenic patients who fail to respond to adequate trials of neuroleptics is a major challenge. Clozapine… Expand
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Highly Cited
1982
Highly Cited
1982
Rats subjected to unilateral ablation of the motor cortex and placed on a narrow beam displayed transient contralateral paresis… Expand
Highly Cited
1963