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Seasonal affective disorder. A description of the syndrome and preliminary findings with light therapy.
Preliminary studies in 11 patients suggest that extending the photoperiod with bright artificial light has an antidepressant effect and sleep recordings in nine depressed patients confirmed the presence of hypersomnia and showed increased sleep latency and reduced slow-wave (delta) sleep.
Automatic sleep/wake identification from wrist activity.
The purpose of this study was to develop and validate automatic scoring methods to distinguish sleep from wakefulness based on wrist activity. Forty-one subjects (18 normals and 23 with sleep or…
Sleep and psychiatric disorders. A meta-analysis.
- R. Benca, W. Obermeyer, R. Thisted, J. Gillin
- Psychology, MedicineArchives of general psychiatry
- 1 August 1992
Although no single sleep variable appeared to have absolute specificity for any particular psychiatric disorder, patterns of sleep disturbances associated with categories of psychiatric illnesses were observed.
Altered brain response to verbal learning following sleep deprivation
- S. Drummond, Gregory G. Brown, J. Gillin, J. L. Stricker, E. Wong, R. Buxton
- Psychology, BiologyNature
- 10 February 2000
It is shown that there are dynamic, compensatory changes in cerebral activation during verbal learning after sleep deprivation and the PFC and parietal lobes are implicated in this compensation.
The sleep of abstinent pure primary alcoholic patients: natural course and relationship to relapse.
- S. Drummond, J. Gillin, T. Smith, A. Demodena
- Medicine, PsychologyAlcoholism, clinical and experimental research
- 1 November 1998
The sleep of abstinent alcoholic patients is short, fragmented, and shallow early in abstinence, and a patient's sleep improves slowly over at least the first year of abstinence; however, some facets of a patients' sleep remain abnormal even after 27 months of abstinence.
Effects of sleep and sleep deprivation on interleukin-6, growth hormone, cortisol, and melatonin levels in humans.
- L. Redwine, R. Hauger, J. Gillin, M. Irwin
- Biology, MedicineThe Journal of clinical endocrinology and…
- 1 October 2000
Sleep stage analyses indicated that the nocturnal increase in IL-6 occurred in association with stage 1-2 sleep and rapid eye movement sleep, but levels during slow wave sleep were not different from those while awake.
Partial night sleep deprivation reduces natural killer and celhdar immune responses in humans
- M. Irwin, Johnathan McClintick, C. Costlow, Melissa Fortner, J. White, J. Gillin
- Biology, MedicineFASEB journal : official publication of the…
- 1 April 1996
Data implicate sleep in the modulation of immunity and demonstrate that even a modest disturbance of sleep produces a reduction of natural immune responses and T cell cytokine production.
Increased cerebral response during a divided attention task following sleep deprivation
This is the first study to examine divided attention performance after TSD with neuroimaging and supports the previous suggestion that the brain may be more plastic during cognitive performance following TSD than previously thought.
Magnetic resonance imaging and mood disorders. Localization of white matter and other subcortical abnormalities.
Patients with bipolar disorder demonstrate a pattern of subcortical brain morphologic abnormalities and cognitive impairment and data indicate that the total volume of abnormal white matter may be associated with increased cognitive impairment, increased rate of psychiatric illness in the family, and onset after adolescence.