HPSE2 protein, human

Known as: heparanase 2 protein, human, Hpa2, heparanase 3 protein, human 
Heparanase-2 (592 aa, ~67 kDa) is encoded by the human HPSE2 gene. This protein is involved in the proteolysis of heparan sulfate proteoglycans.
National Institutes of Health

Topic mentions per year

Topic mentions per year

1995-2018
01219952018

Papers overview

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2016
2016
The proteoglycan syndecan-1 and the endoglucuronidases heparanase-1 and heparanase-2 are involved in molecular pathways that… (More)
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2016
2016
The endoglycosidase heparanase specifically cleaves the heparan sulfate (HS) side chains on proteoglycans, an activity that has… (More)
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2013
2013
AIM Heparanase-2 expression has been suggested to up-regulate in several types of human cancers. However, the expression patterns… (More)
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2013
2013
Urofacial syndrome (UFS) (or Ochoa syndrome) is an autosomal-recessive disease characterized by congenital urinary bladder… (More)
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2011
2011
Various kinds of glycosaminoglycans (GAGs) and proteoglycans (PGs) have been known to be involved in structural and space-filling… (More)
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2011
2011
OBJECTIVE To determine the molecules involved in extracellular matrix remodeling and to identify and quantify heparanase isoforms… (More)
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2009
2009
INTRODUCTION Studies have highlighted the changes that take place in the environment between the cell and the extracellular… (More)
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2008
2008
AIM To propose a quantitative method to detect heparanase-2 (HPA2) and syndecan-1 (Syn-1) using immunohistochemistry in… (More)
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2005
2005
The platelet surface glycoprotein (GP) I balpha, an important part of the GP I b-IX-V complex, participates in the formation of… (More)
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1999
1999
BACKGROUND AND OBJECTIVES Chronic refractory autoimmune thrombocytopenic purpura (AITP) is an autoimmune disorder due to… (More)
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