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HMGB Proteins

Known as: HMGB, HMG-Box Protein, HMG Box Proteins 
The HMG-Box Family proteins are relatively abundant vertebrate DNA-binding and bending proteins that bind with structure specificity, rather than… Expand
National Institutes of Health

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Highly Cited
2017
Highly Cited
2017
Cytosolic DNA arising from intracellular pathogens triggers a powerful innate immune response. It is sensed by cyclic GMP–AMP… Expand
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Highly Cited
2014
Highly Cited
2014
High mobility group box 1 (HMGB1) is a central mediator in inflammation and immunity. Recently, it was shown that different redox… Expand
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Highly Cited
2012
Highly Cited
2012
Osteosarcoma is the most commonly occurring bone cancer in children and adolescents. Unfortunately, treatment failures are common… Expand
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Review
2010
Review
2010
HMGB proteins are members of the High Mobility Group (HMG) superfamily, possessing a unique DNA-binding domain, the HMG-box… Expand
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Review
2010
Review
2010
In eukaryotic nuclei, transcription reactions on the chromatin are regulated by the binding of transcription regulators such as… Expand
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Highly Cited
2010
Highly Cited
2010
The Rockefeller University Press $30.00 J. Cell Biol. Vol. 190 No. 5 881–892 www.jcb.org/cgi/doi/10.1083/jcb.200911078 JCB 881 R… Expand
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Highly Cited
2009
Highly Cited
2009
The activation of innate immune responses by nucleic acids is crucial to protective and pathological immunities and is mediated… Expand
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Highly Cited
2006
Highly Cited
2006
Cerebral ischemic injury proceeds with excitotoxicity-induced acute neuronal death in the ischemic core and with delayed damage… Expand
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Highly Cited
2003
Highly Cited
2003
High mobility group box (HMGB) 1 and 2 are two abundant nonhistone nuclear proteins that have been found in association with… Expand
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Review
1996
Review
1996
Publisher Summary This chapter summarizes recent information on the function of high-mobility-group (HMG) proteins. Advances in… Expand
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