HLCS gene

Known as: HCS, HLCS, HOLOCARBOXYLASE SYNTHETASE 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

1982-2018
0246819822018

Papers overview

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2013
2013
Holocarboxylase synthetase (HCS) catalyzes the binding of the vitamin biotin to histones H3 and H4, thereby creating rare histone… (More)
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2011
2011
Holocarboxylase synthetase (HCS) mediates the binding of biotin to lysine (K) residues in histones H2A, H3 and H4; HCS knockdown… (More)
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2008
2008
BirA ligase is a prokaryotic ortholog of holocarboxylase synthetase (HCS) that can biotinylate proteins. This study tested the… (More)
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2006
2006
Holocarboxylase synthetase deficiency is a rare autosomal recessive disorder of biotin metabolism. Clinical manifestations… (More)
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2004
2004
The attachment of biotin to apocarboxylases is catalyzed by holocarboxylase synthetase (HCS). An inherited deficiency of HCS… (More)
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2004
2004
Holocarboxylase synthetase (HCS) catalyzes the biotinylation of five carboxylases in human cells, and mutations of HCS cause… (More)
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2001
2001
Holocarboxylase synthetase (HLCS) is an enzyme that catalyzes the incorporation of biotin into apo-carboxylases, and its… (More)
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1997
1997
Holocarboxylase synthetase (HCS) is an essential enzyme for the biotinylation of several mammalian carboxylases. A deficiency of… (More)
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1994
1994
Holocarboxylase synthetase (HCS) plays an essential role in biotin utilization in eukaryotic cells and its deficiency causes… (More)
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1982
1982
Two patients with biotin-responsive multiple carboxylase deficiency, both presenting with predominant lactic acidosis, are… (More)
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