Skip to search formSkip to main contentSkip to account menu

HIF1A gene

Known as: HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT, hypoxia inducible factor 1 alpha subunit, MOP1 
This gene plays a role in cardiovascular development and systemic oxygen homeostasis.
National Institutes of Health

Related topics

Related topics

6 relations
Angiogenic ProcessCellular StressHIF1alpha proteinHypoxia-Inducible Factor 1

Narrower (1)

HIF1A wt Allele

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2013
2013
1790 G/A polymorphism, but not 1772 C/T polymorphism, is significantly associated with cancers: an update study.
2012
2012
Genetic polymorphisms in HIF 1 A are associated with prostate cancer risk in a Chinese population
The hypoxia-inducible factor-1a (HIF-1a) plays an important role in regulating angiogenesis, which is essential for tumor growth… 
2010
2010
103 Combination treatment of targeting Stat3 and HIF-1alpha is a potent strategy for prostate cancer therapy
2008
2008
Cloning of miniature pig HIF-1alpha and its responses to immunosuppressive agents.
Miniature pigs are worth notice as candidate donors for xenotransplantation. However, donor organs are inevitably subjected to… 
2007
2007
STAT3, HIF-1alpha, EPO and EPOR - signaling proteins in human primary ductal breast cancers.
STAT3 upregulates expression of HIF-1 induced EPO. Receptor EPOR was reported to activate STAT3. Our study was aimed at… 
2006
2006
Hypoxia-inducible factor 1alpha cDNA cloning and its mRNA and protein tissue specific expression in domestic yak (Bos grunniens) from Qinghai-Tibetan plateau.
Adaptation to hypoxia is regulated by hypoxia-inducible factor 1 (HIF-1), a heterodimeric transcription factor consisting of an… 
2005
2005
[Effect of silencing HIF-1alpha by RNA interference on expression of vascular endothelial growth factor in osteosarcoma cell line SaOS-2 under hypoxia].
BACKGROUND & OBJECTIVE Hypoxia-inducible factor-1 alpha (HIF-1alpha) is a key regulator for hypoxia tolerance and angiogenesis of… 
2004
2004
A novel genetic modifier of p53, mop1, results in embryonic lethality
The heterogeneity that occurs in the tumor spectrum and latency in Li-Fraumeni syndrome (LFS) patients with inherited mutations… 
2004
2004
[Activation of HIF-1 by bFGF in breast cancer: role of PI-3K and MEK1/ERK pathways].
OBJECTIVE To explore the mechanism of basic fibroblast growth factor (bFGF)-mediated hypoxia inducible factor (HIF-1) activation… 
2003
2003
Inducible expression of hypoxia-inducible factor 1alpha (HIF-1alpha) as a tool for studying HIF-1alpha-dependent gene regulation during normoxia in vitro.
The hypoxia-inducible factor 1alpha (HIF-1alpha), a member of the PAS superfamily, is a global regulator of cellular and systemic… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)