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HIF1alpha protein

Known as: Hypoxia-Inducible Factor 1, Alpha Subunit, bHLHe78, Class E Basic Helix-Loop-Helix Protein 78 
Hypoxia-inducible factor 1, alpha subunit is a basic helix-loop-helix transcription factor that is regulated by OXYGEN availability and is targeted… Expand
National Institutes of Health

Papers overview

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Review
2018
Review
2018
It is generally accepted that recent advances in anticancer agents have contributed significantly to the improvement of both the… Expand
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Highly Cited
2004
Highly Cited
2004
The trafficking of circulating stem and progenitor cells to areas of tissue damage is poorly understood. The chemokine stromal… Expand
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Highly Cited
2001
Highly Cited
2001
Hypoxia-inducible factor (HIF) is a transcriptional complex that plays a central role in the regulation of gene expression by… Expand
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Highly Cited
2001
Highly Cited
2001
Hypoxia-inducible factor 1 (HIF-1) is a master regulator of oxygen homeostasis that controls angiogenesis, erythropoiesis, and… Expand
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Highly Cited
2000
Highly Cited
2000
The switch to an angiogenic phenotype is a fundamental determinant of neoplastic growth and tumor progression. We demonstrate… Expand
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Highly Cited
1998
Highly Cited
1998
Hypoxia is an essential developmental and physiological stimulus that plays a key role in the pathophysiology of cancer, heart… Expand
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Highly Cited
1998
Highly Cited
1998
Hypoxia induces a group of physiologically important genes such as erythropoietin and vascular endothelial growth factor. These… Expand
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Highly Cited
1997
Highly Cited
1997
The hypoxia-inducible factor 1 transcriptional activator complex (HIF-1) is involved in the activation of the erythropoietin and… Expand
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Highly Cited
1997
Highly Cited
1997
Here we describe the cloning and characterization of a PAS domain transcription factor termed endothelial PAS-1 (EPAS1). This… Expand
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Highly Cited
1996
Highly Cited
1996
Expression of vascular endothelial growth factor (VEGF) is induced in cells exposed to hypoxia or ischemia. Neovascularization… Expand
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