HIF1alpha protein

Known as: Hypoxia-Inducible Factor 1, Alpha Subunit, bHLHe78, Class E Basic Helix-Loop-Helix Protein 78 
Hypoxia-inducible factor 1, alpha subunit is a basic helix-loop-helix transcription factor that is regulated by OXYGEN availability and is targeted… (More)
National Institutes of Health

Papers overview

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Highly Cited
2008
Highly Cited
2008
Stabilization of the hypoxia-inducible factor-1α (HIF-1α) transcription complex, caused by intratumoural hypoxia, promotes tumour… (More)
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Review
2006
Review
2006
Adaptation to low oxygen tension (hypoxia) in cells and tissues leads to the transcriptional induction of a series of genes that… (More)
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Highly Cited
2005
Highly Cited
2005
In addition to controlling a switch to glycolytic metabolism and induction of erythropoiesis and angiogenesis, hypoxia promotes… (More)
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Highly Cited
2003
Highly Cited
2003
Granulocytes and monocytes/macrophages of the myeloid lineage are the chief cellular agents of innate immunity. Here, we have… (More)
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Highly Cited
2001
Highly Cited
2001
Hypoxia-inducible factor (HIF) is a transcriptional complex that plays a central role in the regulation of gene expression by… (More)
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Highly Cited
2001
Highly Cited
2001
Hypoxia-inducible factor 1 (HIF-1) is a master regulator of oxygen homeostasis that controls angiogenesis, erythropoiesis, and… (More)
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Highly Cited
1998
Highly Cited
1998
Hypoxia induces a group of physiologically important genes such as erythropoietin and vascular endothelial growth factor. These… (More)
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Highly Cited
1997
Highly Cited
1997
The hypoxia-inducible factor 1 transcriptional activator complex (HIF-1) is involved in the activation of the erythropoietin and… (More)
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Highly Cited
1997
Highly Cited
1997
Here we describe the cloning and characterization of a PAS domain transcription factor termed endothelial PAS-1 (EPAS1). This… (More)
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Highly Cited
1996
Highly Cited
1996
Expression of vascular endothelial growth factor (VEGF) is induced in cells exposed to hypoxia or ischemia. Neovascularization… (More)
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