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Guanethidine

Known as: Oktadin, (2-(hexahydro-1(2h)-azocinyl)ethyl)guanidine, guanéthidine 
An antihypertensive agent that acts by inhibiting selectively transmission in post-ganglionic adrenergic nerves. It is believed to act mainly by… Expand
National Institutes of Health

Papers overview

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Review
2007
Review
2007
Neurons in the dorsomedial hypothalamus (DMH) play key roles in physiological responses to exteroceptive ("emotional") stress in… Expand
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Highly Cited
2005
Highly Cited
2005
The hypernociceptive effects of cytokines [TNF-alpha, keratinocyte-derived chemokine (KC), and IL-1beta] and their participation… Expand
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Highly Cited
2003
Highly Cited
2003
We studied whether physiological concentration of short-chain fatty acids (SCFAs) affects colonic transit and colonic motility in… Expand
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Highly Cited
1998
Highly Cited
1998
The generation of knock-out and transgenic mice offers a promising approach to the identification of novel biochemical factors… Expand
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Highly Cited
1995
Highly Cited
1995
This double-blind, randomized, multicenter study was designed to determine the short-term and long-term efficacy of intravenous… Expand
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Highly Cited
1992
Highly Cited
1992
BACKGROUND Nitric oxide has been identified as an endothelium-derived relaxing factor in blood vessels. We tried to determine… Expand
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Highly Cited
1990
Highly Cited
1990
In the presence of functional adrenergic and cholinergic blockade, electrical field stimulation relaxes corpus cavernosum smooth… Expand
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Highly Cited
1988
Highly Cited
1988
We investigated the participation of a sympathetic component in the abdominal contortions induced by intraperitoneal injection of… Expand
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Highly Cited
1979
Highly Cited
1979
Summary1.Antidromic vasodilation and neurogenic plasma extravasation were induced by antidromic stimulation of the saphenous… Expand
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Highly Cited
1976
Highly Cited
1976
The studies were performed on operation material from 17- to 63-year-old patients and on fetuses at 19-23 weeks gestational age… Expand
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