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Guanethidine

Known as: Oktadin, (2-(hexahydro-1(2h)-azocinyl)ethyl)guanidine, guanéthidine 
An antihypertensive agent that acts by inhibiting selectively transmission in post-ganglionic adrenergic nerves. It is believed to act mainly by… 
National Institutes of Health

Related topics

Related topics

27 relations

Broader (6)

Adrenergic AgentsAminesAntihypertensive AgentsGuanidine
Adrenergic alpha2-Agonists [MoA]Congestive heart failureDecreased Blood Pressure [PE]Guanethidine Sulfate

Narrower (6)

EsimilGuanethidine MonosulfateIsmelinIsobarin

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2006
Review
2006
Physiology and Pharmacology of Temperature Regulation The dorsomedial hypothalamus : a new player in thermoregulation
id 13940&is_tech 0] 49. DiMicco JA, Soltis RP, Anderson JJ, and Wible JH Jr. Hypothalamic mechanisms and the cardiovascular… 
Highly Cited
1992
Highly Cited
1992
Nitric Oxide as a Mediator of Relaxation of the Corpus Cavernosum in Response to Nonadrenergic, Noncholinergic Neurotransmission
Abstract Background. Nitric oxide has been identified as an endothelium-derived relaxing factor in blood vessels. We tried to… 
Highly Cited
1989
Highly Cited
1989
Regional sympathetic denervation after myocardial infarction in humans detected noninvasively using I-123-metaiodobenzylguanidine.
Highly Cited
1988
Highly Cited
1988
Stimulation of afferent nerve endings by intragastric capsaicin protects against ethanol-induced damage of gastric mucosa
Highly Cited
1986
Highly Cited
1986
Gastric mucosal protection against ulcerogenic factors in the rat mediated by capsaicin-sensitive afferent neurons.
Highly Cited
1982
Highly Cited
1982
Atropine resistance of transmurally stimulated isolated human bladder muscle.
Highly Cited
1982
Highly Cited
1982
Neurons with 5-hydroxytryptamine-like immunoreactivity in the enteric nervous system: Their visualization and reactions to drug treatment
Highly Cited
1976
Highly Cited
1976
Autonomic nerves, mast cells, and amine receptors in human brain vessels. A histochemical and pharmacological study
Highly Cited
1971
Highly Cited
1971
Evidence against adrenergic motor transmission in the guinea‐pig vas deferens
1. Field stimulation of desheathed preparations of guinea‐pig vas deferens, treated with a ganglion‐blocking agent, has revealed… 
Highly Cited
1966
Highly Cited
1966
The inhibitory innervation of the taenia of the guinea‐pig caecum
1. The inhibitory innervation of the taenia of the guinea‐pig caecum has been studied, after blocking the responses to… 
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