Guanethidine

Known as: Oktadin, (2-(hexahydro-1(2h)-azocinyl)ethyl)guanidine, guanéthidine 
An antihypertensive agent that acts by inhibiting selectively transmission in post-ganglionic adrenergic nerves. It is believed to act mainly by… (More)

Topic mentions per year

Topic mentions per year

1952-2017
05019522016

Papers overview

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Highly Cited
1998
Highly Cited
1998
The generation of knock-out and transgenic mice offers a promising approach to the identification of novel biochemical factors… (More)
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1995
1995
This double-blind, randomized, multicenter study was designed to determine the short-term and long-term efficacy of intravenous… (More)
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Highly Cited
1992
Highly Cited
1992
BACKGROUND Nitric oxide has been identified as an endothelium-derived relaxing factor in blood vessels. We tried to determine… (More)
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Highly Cited
1990
Highly Cited
1990
In the presence of functional adrenergic and cholinergic blockade, electrical field stimulation relaxes corpus cavernosum smooth… (More)
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1983
1983
Regional intravenous guanethidine blocks and stellate ganglion blocks have been compared in a randomized trial. Nineteen patients… (More)
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1981
1981
Thirty-one patients with pain in one or both hands associated with sympathetic dystrophy or Raynaud's disease were studied before… (More)
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Highly Cited
1979
Highly Cited
1979
1. Antidromic vasodilation and neurogenic plasma extravasation were induced by antidromic stimulation of the saphenous nerve in… (More)
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1977
1977
17 consecutive cases of Sudeck's atrophy were treated with intravenous regional guanethidine. Results were encouraging… (More)
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Highly Cited
1976
Highly Cited
1976
The studies were performed on operation material from 17- to 63-year-old patients and on fetuses at 19-23 weeks gestational age… (More)
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1976
1976
The administration of guanethidine to newborn rats has been shown to produce a permanent sympathectomy with potential advantages… (More)
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