Guanidine

Known as: Aminomethanamidine, Guanidinium, Guanidines 
A strong organic base existing primarily as guanidium ions at physiological pH. It is found in the urine as a normal product of protein metabolism… (More)
National Institutes of Health

Related topics

Related topics

42 relations

Narrower (32)

4,5-biphenyl-2-pyrimidinylguanidineChlorhexidineCimetidineCocospropylenediamine-guanidinium diacetate
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Broader (2)

AmidinesGuanidines
Guanidine Hydrochloride 125 MG Oral TabletIn Bloodagonistsanalogs & derivatives
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Papers overview

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Review
2018
Review
2018
Oxidative stress and reactive oxygen species in endothelial dysfunction associated with cardiovascular and metabolic diseases.
Reactive oxygen species (ROS) are reactive intermediates of molecular oxygen that act as important second messengers within the… (More)
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Review
2017
Review
2017
Metformin: historical overview
Metformin (dimethylbiguanide) has become the preferred first-line oral blood glucose-lowering agent to manage type 2 diabetes… (More)
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Highly Cited
2002
Highly Cited
2002
Arsenic mobility and groundwater extraction in Bangladesh.
High levels of arsenic in well water are causing widespread poisoning in Bangladesh. In a typical aquifer in southern Bangladesh… (More)
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Highly Cited
2002
Highly Cited
2002
A common mechanism underlying promiscuous inhibitors from virtual and high-throughput screening.
High-throughput and virtual screening are widely used to discover novel leads for drug design. On examination, many screening… (More)
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Highly Cited
2000
Highly Cited
2000
The design, synthesis, and evaluation of molecules that enable or enhance cellular uptake: peptoid molecular transporters.
Certain proteins contain subunits that enable their active translocation across the plasma membrane into cells. In the specific… (More)
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Highly Cited
1998
Highly Cited
1998
Claudin-1 and -2: Novel Integral Membrane Proteins Localizing at Tight Junctions with No Sequence Similarity to Occludin
Occludin is the only known integral membrane protein localizing at tight junctions (TJ), but recent targeted disruption analysis… (More)
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Highly Cited
1993
Highly Cited
1993
Thioflavine T interaction with synthetic Alzheimer's disease beta-amyloid peptides: detection of amyloid aggregation in solution.
Thioflavine T (ThT) associates rapidly with aggregated fibrils of the synthetic beta/A4-derived peptides beta(1-28) and beta(1-40… (More)
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Highly Cited
1992
Highly Cited
1992
High resistance to cisplatin in human ovarian cancer cell lines is associated with marked increase of glutathione synthesis.
Exposure of human ovarian tumor cell lines to cisplatin led to development of cell lines that exhibited increasing degrees of… (More)
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Highly Cited
1987
Highly Cited
1987
Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction.
A new method of total RNA isolation by a single extraction with an acid guanidinium thiocyanate-phenol-chloroform mixture is… (More)
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Highly Cited
1984
Highly Cited
1984
Alzheimer's disease: initial report of the purification and characterization of a novel cerebrovascular amyloid protein.
A purified protein derived from the twisted beta-pleated sheet fibrils in cerebrovascular amyloidosis associated with Alzheimer's… (More)
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