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Cimetidine

Known as: 1-Cyano-2-methyl-3-(2-(((5-methyl-4-imidazolyl)methyl)thio)ethyl)guanidine, N-Cyano-N'-methyl-N''-[2-[[(5-methyl-1H-imidazol-4-yl)methyl]thio]ethyl]guanidine, N-Cyano-N'-methyl-N''-(2-(((5-methyl-1H-imidazol-4-yl)methyl)thio)ethyl)guanidine 
A histamine H(2)-receptor antagonist. Enhancing anti-tumor cell-mediated responses, cimetidine blocks histamine's ability to stimulate suppressor T… Expand
National Institutes of Health

Papers overview

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Highly Cited
2007
Highly Cited
2007
Pharmaceuticals are manufactured and used for specific biological functions in veterinary and human medicine. Their detection in… Expand
Highly Cited
2000
Highly Cited
2000
A series of new nitrogen-carbon-linked (azolylphenyl)oxazolidinone antibacterial agents has been prepared in an effort to expand… Expand
Highly Cited
1996
Highly Cited
1996
BACKGROUND: Gastric and duodenal bacterial overgrowth frequently occurs in conditions where diminished acid secretion is present… Expand
Highly Cited
1988
Highly Cited
1988
100 consecutive patients with both duodenal ulcer and Campylobacter pylori infection were followed up to see whether eradication… Expand
Highly Cited
1987
Highly Cited
1987
To determine whether cimetidine altered the renal handling of metformin, seven subjects took 0.25 g metformin daily with and… Expand
Highly Cited
1985
Highly Cited
1985
To determine the reliability of creatinine as a measure of the glomerular filtration rate (GFR), we compared the simultaneous… Expand
Highly Cited
1981
Highly Cited
1981
We studied the influence of cimetidine on liver blood flow in eight normal subjects. Cimetidine acutely reduced liver blood flow… Expand
Highly Cited
1981
Highly Cited
1981
One hour of regional ischemia significantly increases the permeability of intestinal capillaries. The role of local humoral… Expand
Highly Cited
1979
Highly Cited
1979
The effect of representative agents of three classes of antisecretory compounds; prostaglandins, histamine H2-receptor antagonist… Expand
Highly Cited
1975
Highly Cited
1975
Cimetidine is a non-thiourea analogue of metiamide. It is a specific competitive histamine H2-receptor antagonist and is an… Expand
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