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Cimetidine

Known as: 1-Cyano-2-methyl-3-(2-(((5-methyl-4-imidazolyl)methyl)thio)ethyl)guanidine, N-Cyano-N'-methyl-N''-[2-[[(5-methyl-1H-imidazol-4-yl)methyl]thio]ethyl]guanidine, N-Cyano-N'-methyl-N''-(2-(((5-methyl-1H-imidazol-4-yl)methyl)thio)ethyl)guanidine 
A histamine H(2)-receptor antagonist. Enhancing anti-tumor cell-mediated responses, cimetidine blocks histamine's ability to stimulate suppressor T… Expand
National Institutes of Health

Papers overview

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Highly Cited
2011
Highly Cited
2011
A systematic computational method predicts new uses for existing drugs by integrating public gene expression signatures of drugs… Expand
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Highly Cited
2009
Highly Cited
2009
In human proximal tubules, organic cations are taken up from blood into cells by human organic cation transporter 2 [hOCT2/solute… Expand
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Highly Cited
2008
Highly Cited
2008
PURPOSE Genetic polymorphisms of organic cation transporter 2 (OCT2) have been recently described, but their genotype-phenotype… Expand
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Highly Cited
2007
Highly Cited
2007
Pharmaceuticals are manufactured and used for specific biological functions in veterinary and human medicine. Their detection in… Expand
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Highly Cited
2005
Highly Cited
2005
The present study involves preparation and evaluation of floating microspheres with cimetidine as model drug for prolongation of… Expand
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Highly Cited
2003
Highly Cited
2003
The photochemical fates of the histamine H2-receptor antagonists cimetidine and ranitidine were studied. Each of the two… Expand
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Review
2002
Review
2002
Insulin resistance contributes greatly to development of cardiovascular disease in patients with the metabolic syndrome and its… Expand
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Highly Cited
1996
Highly Cited
1996
BACKGROUND: Gastric and duodenal bacterial overgrowth frequently occurs in conditions where diminished acid secretion is present… Expand
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Highly Cited
1987
Highly Cited
1987
To determine whether cimetidine altered the renal handling of metformin, seven subjects took 0.25 g metformin daily with and… Expand
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Highly Cited
1985
Highly Cited
1985
To determine the reliability of creatinine as a measure of the glomerular filtration rate (GFR), we compared the simultaneous… Expand
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