Cimetidine

Known as: 1-Cyano-2-methyl-3-(2-(((5-methyl-4-imidazolyl)methyl)thio)ethyl)guanidine, N-Cyano-N'-methyl-N''-[2-[[(5-methyl-1H-imidazol-4-yl)methyl]thio]ethyl]guanidine, N-Cyano-N'-methyl-N''-(2-(((5-methyl-1H-imidazol-4-yl)methyl)thio)ethyl)guanidine 
A histamine H(2)-receptor antagonist. Enhancing anti-tumor cell-mediated responses, cimetidine blocks histamine's ability to stimulate suppressor T… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1950-2017
020040019502016

Papers overview

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Highly Cited
2008
Highly Cited
2008
PURPOSE Genetic polymorphisms of organic cation transporter 2 (OCT2) have been recently described, but their genotype-phenotype… (More)
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Highly Cited
2007
Highly Cited
2007
Pharmaceuticals are manufactured and used for specific biological functions in veterinary and human medicine. Their detection in… (More)
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Highly Cited
2005
Highly Cited
2005
The breast cancer resistance protein (BCRP/ABCG2) is an ATP-binding cassette drug efflux transporter that extrudes xenotoxins… (More)
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Highly Cited
1996
Highly Cited
1996
BACKGROUND Gastric and duodenal bacterial overgrowth frequently occurs in conditions where diminished acid secretion is present… (More)
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Highly Cited
1996
Highly Cited
1996
Probenazole (3-allyloxy-1,2-benzisothiazole-1,1-dioxide) induces disease resistance in rice against rice blast fungus. To… (More)
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Highly Cited
1988
Highly Cited
1988
100 consecutive patients with both duodenal ulcer and Campylobacter pylori infection were followed up to see whether eradication… (More)
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Highly Cited
1987
Highly Cited
1987
To determine whether cimetidine altered the renal handling of metformin, seven subjects took 0.25 g metformin daily with and… (More)
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Highly Cited
1985
Highly Cited
1985
To determine the reliability of creatinine as a measure of the glomerular filtration rate (GFR), we compared the simultaneous… (More)
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Highly Cited
1979
Highly Cited
1979
Oral administration to fasted rats of either absolute ethanol, 0.6 N hydrochloric acid, 0.2 N sodium hydroxide, 25% sodium… (More)
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Highly Cited
1979
Highly Cited
1979
1. Antidromic vasodilation and neurogenic plasma extravasation were induced by antidromic stimulation of the saphenous nerve in… (More)
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