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Cimetidine

Known as: 1-Cyano-2-methyl-3-(2-(((5-methyl-4-imidazolyl)methyl)thio)ethyl)guanidine, N-Cyano-N'-methyl-N''-[2-[[(5-methyl-1H-imidazol-4-yl)methyl]thio]ethyl]guanidine, N-Cyano-N'-methyl-N''-(2-(((5-methyl-1H-imidazol-4-yl)methyl)thio)ethyl)guanidine 
A histamine H(2)-receptor antagonist. Enhancing anti-tumor cell-mediated responses, cimetidine blocks histamine's ability to stimulate suppressor T… 
National Institutes of Health

Related topics

Related topics

41 relations
12 HR Propafenone Hydrochloride 225 MG Extended Release Oral CapsuleCimetidine:PrThr:Pt:Ser/Plas:OrdCimetidine:PrThr:Pt:Urine:OrdCimetidine:PrThr:Pt:XXX:Ord

Narrower (8)

AltrametCimetidine HydrochloridePoly-5SKF 92374

Broader (6)

Anti-Ulcer AgentAntihistaminesGuanidineGuanidines

Papers overview

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1992
1992
Comparison of KRN2391 with Nicorandil and Nifedipine on Canine Coronary Blood Flow: Antagonism by Glibenclamide
Summary: The mode of action of KRN2391 [N-cyano-N‘-(2-nitroxyethyl)-3-pyridinecarboximidamide monomethanesulfonate] in coronary… 
Highly Cited
1988
Highly Cited
1988
Effect of cimetidine on inhibition by tetragastrin of carcinogenesis induced by N-methyl-N'-nitro-N-nitrosoguanidine in Wistar rats.
The effects of combined administration of cimetidine and tetragastrin on gastric acid secretion, the labeling index of the… 
1987
1987
Synthesis and calcium channel antagonist activity of dialkyl 4- (dihydropyridinyl)-1,4-dihydro-2,6-dimethyl-3,5-pyridinecarboxylates.
The sodium borohydride reduction of 3,5-disubstituted 1,4-dihydro-2,6-dimethyl-4-(pyridinyl)pyridines 2 and 5 in the presence of… 
1986
1986
Synthesis and calcium channel antagonist activity of dialkyl 1,4-dihydro-2,6-dimethyl-4-(pyridinyl)-3,5-pyridinedicarboxylates.
The Hantzsch condensation of alkyl acetoacetates 3 with methyl 3-aminocrotonate (4) and pyridinecarboxaldehydes 5 afforded the… 
1986
1986
Gastroesophageal reflux disease. Acute and maintenance treatments with cimetidine.
The comparative efficacy of a 12-week acute treatment with 800 and 1600 mg cimetidine daily and the effectiveness of a 400-mg… 
1986
1986
Dipole moment in relation to H2 receptor histamine antagonist activity for cimetidine analogues.
The activities of a series of H2 receptor histamine antagonists structurally related to cimetidine (1) have been compared to… 
1982
1982
The metabolism of [14C]cimetidine in man.
1. The excretion and metabolism of [2-(14)C]cimetidine (500 mg orally) was studied in five male volunteers. 2. Over 70% of the… 
1981
1981
Cimetidine interaction with carbamazepine.
Excerpt To the editor: A recent report of Desmond and colleagues (1) showed delayed clearance of diazepam due to cimetidine… 
1981
1981
Cimetidine in the treatment of gastric ulcer induced by steroidal and nonsteroidal anti-inflammatory agents.
The study of a group of patients with gastric ulcers induced by anti-inflammatory agents, was undertaken in an attempt to… 
1976
1976
Preparation and properties of S-cyano derivatives of creatine kinase.
The two reactive thiol groups of rabbit muscle creatine kinase were stoichiometrically reacted with 5,5'-dithio-bis(2…