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STEAP: a prostate-specific cell-surface antigen highly expressed in human prostate tumors.
TLDR
The results support STEAP as a cell-surface tumor-antigen target for prostate cancer therapy and diagnostic imaging and support its role as a channel or transporter protein. Expand
Trimethylaminuria: the fish malodor syndrome.
TLDR
Progress has been made at all levels-clinical, epidemiological, biochemical, and genetic-in understanding of the fish malodor syndrome, and the current needs in the treatment of patients are highlighted. Expand
The exogenous origin of trimethylamine in the mouse.
TLDR
C Cohabitation of germ-free mice with conventional animals restored their ability to excrete TMA and invokes a fundamental role for the intestinal microflora in the provision of TMA from precursors within the food. Expand
The disposition of allyl isothiocyanate in the rat and mouse.
TLDR
Examination of the urinary bladders of male and female rats following oral dosing with [14C]AITC showed a sex difference with greater amounts of AITC and/or its metabolites within the bladder tissue of male rats, in a carcinogenicity study conducted by the National Toxicology Program in the USA. Expand
Dietary precursors of trimethylamine in man: a pilot study.
TLDR
Of 46 different foods investigated, only fish and other sea-products gave rise to significant increases in urinary trimethylamine and N-oxide and ingestion of fruits, vegetables, cereal and dairy produce, and meats had no measurable effects. Expand
Studies on the discontinuous N-oxidation of trimethylamine among Jordanian, Ecuadorian and New Guinean populations.
TLDR
Observations suggest that a compromised ability to N-oxidize trimethylamine is detectable in several ethnic groups and that this polymorphic phenomenon may have a widespread existence. Expand
Disclosure of the metabolic retroversion of trimethylamine N‐oxide in humans: A pharmacogenetic approach
TLDR
It is proposed that the use of human metabolic variants allows both a qualitative and quantitative assessment of retroverted metabolism as occurs with TMAO, and the principle may usefully be applied in other situations. Expand
S-Methyl-L-cysteine sulphoxide: the Cinderella phytochemical?
TLDR
This review aims to consolidate current knowledge surrounding this amino acid derivative, S-methyl-L-cysteine sulphoxide, and provide an impetus for its further examination. Expand
Plastic contamination of the food chain: A threat to human health?
TLDR
Studies using nanoparticles of other materials suggest that toxicity could potentially affect the central nervous system and the reproductive system, although this would be unlikely unless exposure levels were very high and absorption was increased by physiological factors. Expand
A Genetic polymorphism of the N‐oxidation of trimethylamine in humans
TLDR
The study of the families of the two propositi, as well as those of two identified subjects with trimethylaminuria, under both normal dietary conditions and after oral TMA challenge strongly indicates that the conditions of impaired N‐oxidation is inherited as a recessive trait. Expand
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