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Chlorhexidine

Known as: Chlorhexidine [Chemical/Ingredient], 2,4,11,13-Tetraazatetradecanediimidamide, N,N''-bis(4-chlorophenyl)-3,12-diimino-, 1,1'-Hexamethylene bis(5-(P-chlorophenyl)biguanide) 
A biguanide compound used as an antiseptic agent with topical antibacterial activity. Chlorhexidine is positively charged and reacts with the… 
National Institutes of Health

Papers overview

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Highly Cited
2013
Highly Cited
2013
BACKGROUND Results of previous single-center, observational studies suggest that daily bathing of patients with chlorhexidine may… 
Highly Cited
2010
Highly Cited
2010
BACKGROUND Since the patient's skin is a major source of pathogens that cause surgical-site infection, optimization of… 
Review
2009
Review
2009
Microorganisms and their by-products are considered to be the major cause of pulp and periradicular pathosis. Hence, a major… 
Highly Cited
2007
Highly Cited
2007
Host-derived proteases have been reported to degrade the collagen matrix of incompletely-resin-infiltrated dentin. This study… 
Highly Cited
2007
Highly Cited
2007
Loss of hybrid layer integrity compromises resin-dentin bond stability. Matrix metalloproteinases (MMPs) may be partially… 
Highly Cited
2005
Highly Cited
2005
The recent paradigm that endogenous collagenolytic and gelatinolytic activities derived from acid-etched dentin result in… 
Highly Cited
1999
Highly Cited
1999
ABSTRACT Matrix metalloproteinases (MMPs) are a host cell-derived proteolytic enzyme family which plays a major role in tissue… 
Review
1997
Review
1997
  • C. Jones
  • Periodontology
  • 1997
  • Corpus ID: 46358029
After 20 years of use by the dental profession, chlorhexidine is recognized as the gold standard against which other antiplaque… 
Review
1986
Review
1986
  • M. Addy
  • Journal of clinical periodontology
  • 1986
  • Corpus ID: 10441590
Based on the association of bacterial plaque with the initiation of chronic gingivitis and progression of chronic periodontitis…