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Chlorhexidine

Known as: Chlorhexidine [Chemical/Ingredient], 2,4,11,13-Tetraazatetradecanediimidamide, N,N''-bis(4-chlorophenyl)-3,12-diimino-, 1,1'-Hexamethylene bis(5-(P-chlorophenyl)biguanide) 
A biguanide compound used as an antiseptic agent with topical antibacterial activity. Chlorhexidine is positively charged and reacts with the… 
National Institutes of Health

Related topics

Related topics

47 relations

Broader (5)

Anti-Infective AgentsDisinfectantsGuanidineGuanidines
AntibioticsCHLORHEXIDINE DIACETATE .005 kg in 1 kg TOPICAL POWDER [FROST-PROOF]Cetrimide / ChlorhexidineChlorhexidine / silver sulfadiazine

Narrower (13)

Calgon VestaLPD gingival message agentMK-412AMal-A-Ket

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2013
Highly Cited
2013
Effect of daily chlorhexidine bathing on hospital-acquired infection.
BACKGROUND Results of previous single-center, observational studies suggest that daily bathing of patients with chlorhexidine may… 
Highly Cited
2010
Highly Cited
2010
Chlorhexidine-Alcohol versus Povidone-Iodine for Surgical-Site Antisepsis.
BACKGROUND Since the patient's skin is a major source of pathogens that cause surgical-site infection, optimization of… 
Review
2009
Review
2009
The properties and applications of chlorhexidine in endodontics.
Microorganisms and their by-products are considered to be the major cause of pulp and periradicular pathosis. Hence, a major… 
Highly Cited
2007
Highly Cited
2007
In vivo Preservation of the Hybrid Layer by Chlorhexidine
Host-derived proteases have been reported to degrade the collagen matrix of incompletely-resin-infiltrated dentin. This study… 
Highly Cited
2007
Highly Cited
2007
Chlorhexidine Preserves Dentin Bond in vitro
Loss of hybrid layer integrity compromises resin-dentin bond stability. Matrix metalloproteinases (MMPs) may be partially… 
Review
2006
Review
2006
Enterococcus faecalis: its role in root canal treatment failure and current concepts in retreatment.
Highly Cited
2005
Highly Cited
2005
Chlorhexidine Arrests Subclinical Degradation of Dentin Hybrid Layers in vivo
The recent paradigm that endogenous collagenolytic and gelatinolytic activities derived from acid-etched dentin result in… 
Highly Cited
1999
Highly Cited
1999
Inhibition of the Activities of Matrix Metalloproteinases 2, 8, and 9 by Chlorhexidine
ABSTRACT Matrix metalloproteinases (MMPs) are a host cell-derived proteolytic enzyme family which plays a major role in tissue… 
Review
1997
Review
1997
Chlorhexidine: is it still the gold standard?
  • C. Jones
  • Periodontology
  • 1997
  • Corpus ID: 46358029
After 20 years of use by the dental profession, chlorhexidine is recognized as the gold standard against which other antiplaque… 
Review
1986
Review
1986
Chlorhexidine compared with other locally delivered antimicrobials. A short review.
  • M. Addy
  • Journal of clinical periodontology
  • 1986
  • Corpus ID: 10441590
Based on the association of bacterial plaque with the initiation of chronic gingivitis and progression of chronic periodontitis… 
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