FAQ

Chlorhexidine

Known as: Chlorhexidine [Chemical/Ingredient], 2,4,11,13-Tetraazatetradecanediimidamide, N,N''-bis(4-chlorophenyl)-3,12-diimino-, 1,1'-Hexamethylene bis(5-(P-chlorophenyl)biguanide) 
A biguanide compound used as an antiseptic agent with topical antibacterial activity. Chlorhexidine is positively charged and reacts with the… (More)

Topic mentions per year

Topic mentions per year

1955-2018
020040060019552017

Related topics

Related topics

47 relations

Narrower (27)

AccleanAvagardCHX PlusChlorhexidine diacetate
(More)

Broader (6)

Anti-Infective AgentsAnti-Infective Agents, LocalAntibioticsDisinfectants
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Chlorhexidine / silver sulfadiazineChlorhexidine HydrochlorideChlorhexidine MouthwashDrug Allergy
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Related mentions per year

Related mentions per year

1936-2018
19401960198020002020
Chlorhexidine
Drug Allergy
Antibiotics
Periodontal Diseases
Anti-Infective Agents, Local
Disinfectants

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2013
Highly Cited
2013
Effect of daily chlorhexidine bathing on hospital-acquired infection.
BACKGROUND Results of previous single-center, observational studies suggest that daily bathing of patients with chlorhexidine may… (More)
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Highly Cited
2010
Highly Cited
2010
Chlorhexidine-Alcohol versus Povidone-Iodine for Surgical-Site Antisepsis.
BACKGROUND Since the patient's skin is a major source of pathogens that cause surgical-site infection, optimization of… (More)
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Highly Cited
2007
Highly Cited
2007
Chlorhexidine preserves dentin bond in vitro.
Loss of hybrid layer integrity compromises resin-dentin bond stability. Matrix metalloproteinases (MMPs) may be partially… (More)
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Highly Cited
2007
Highly Cited
2007
In vivo preservation of the hybrid layer by chlorhexidine.
Host-derived proteases have been reported to degrade the collagen matrix of incompletely-resin-infiltrated dentin. This study… (More)
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Highly Cited
2006
Highly Cited
2006
Oral decontamination with chlorhexidine reduces the incidence of ventilator-associated pneumonia.
RATIONALE Ventilator-associated pneumonia (VAP) is the most frequently occurring nosocomial infection associated with increased… (More)
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Highly Cited
2005
Highly Cited
2005
Chlorhexidine arrests subclinical degradation of dentin hybrid layers in vivo.
The recent paradigm that endogenous collagenolytic and gelatinolytic activities derived from acid-etched dentin result in… (More)
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Highly Cited
2003
Highly Cited
2003
Effectiveness of 2% chlorhexidine gel and calcium hydroxide against Enterococcus faecalis in bovine root dentine in vitro.
AIM To evaluate the effectiveness of 2% chlorhexidine gluconate gel and calcium hydroxide (Ca(OH)2) as intracanal medicaments… (More)
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Highly Cited
2001
Highly Cited
2001
In vitro antimicrobial activity of several concentrations of sodium hypochlorite and chlorhexidine gluconate in the elimination of Enterococcus faecalis.
AIM The aim of this study was to assess, in vitro, the effectiveness of several concentrations of NaOCl (0.5%, 1%, 2.5%, 4% and 5… (More)
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Highly Cited
1999
Highly Cited
1999
Inhibition of the activities of matrix metalloproteinases 2, 8, and 9 by chlorhexidine.
Matrix metalloproteinases (MMPs) are a host cell-derived proteolytic enzyme family which plays a major role in tissue-destructive… (More)
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Highly Cited
1991
Highly Cited
1991
Prospective randomised trial of povidone-iodine, alcohol, and chlorhexidine for prevention of infection associated with central venous and arterial catheters.
More than 90% of all intravascular device-related septicaemias are due to central venous or arterial catheters. To assess the… (More)
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