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Amidines

Known as: Amidines [Chemical/Ingredient], amidine 
Derivatives of oxoacids RnE(=O)OH in which the hydroxy group is replaced by an amino group and the oxo group is replaced by =NR. Amidines include… 
National Institutes of Health

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1-acetylhydrazinylthiophene formamidine2-chloroacetamidine3,5-dimethylpyrazole-1-carboxamidine4-amidinoindan-1-one 2'-amidinohydrazone
In BloodNitrogen Compounds, Unspecifiedagonistsantagonists & inhibitors

Broader (1)

Organic Chemicals

Papers overview

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2010
2010
Synthesis and Antiinflammatory Activity Evaluation of Some Sulfonamide and Amidine Derivatives of 4-Aryl-3-(2 or 4-picolyl)-2-imino-4-thiazolines.
Condensation of 2- and 4-picolylaminehydrochloride 2a,b with (un) substituted phenacylthiocyanate 1a-d gives 4-aryl-3-(2- or 4… 
2005
2005
Condensation of vaporous amino acids in the presence of silica. Formation of bi- and tricyclic amidines
Amino acids (alanine, valine, norvaline, leucine, and 2-aminoisobutyric acid) were subjected to repeated (5–9 times) sublimation… 
2002
2002
Reactions with heterocyclic amidines: New routes for the synthesis of novel azolo[1,5-a]pyrimidine, benzo[4,5]imidazo[1,2-a]pyrimidine, some pyridine, pyran and pyrazole derivatives containing the…
Some novel pyrazolo[1,5-a]pyrimidines 5a,e, 1,2,4-triazolo[1,5-a]pyrimidine 10 and benzo[4,5]imidazo[1,2-a]pyrimidine 15 could be… 
Highly Cited
1996
Highly Cited
1996
2-Iminopiperidine and other 2-iminoazaheterocycles as potent inhibitors of human nitric oxide synthase isoforms.
A series of 2-iminoazaheterocycles have been prepared and shown to be potent inhibitors of human nitric oxide synthase (NOS… 
1988
1988
Synthesis and copper-dependent antimycoplasmal activity of 1-amino-3-(2-pyridyl)isoquinoline derivatives. 2. Amidines.
In our search for new compounds with antimycoplasmal activity, a series of aromatic amidines derived from 1-amino-3-(2-pyridyl… 
1986
1986
Quantitative structure-activity relationships and molecular graphics in ligand receptor interactions: amidine inhibition of trypsin.
Quantitative structure-activity relationships have been formulated for four sets of amidine inhibitors of trypsin. The… 
1984
1984
Histamine H2 receptor antagonists. 1. Synthesis of N-cyano and N-carbamoyl amidine derivatives and their biological activities.
A large number of N-cyano amidine derivatives were prepared as potential histamine H2 receptor antagonists and evaluated for… 
1983
1983
Cardiac-slowing amidines containing the 3-thioindone group. Potential antianginal agents.
A series of 3-thioindolamidines (and 3-indolamidines) related to mixidine (1) was studied for cardiac-slowing properties… 
1975
1975
Amidines and related compounds. 6. Studies on structure-activity relationships of antihypertensive and antisecretory agents related to clonidine.
Correlations of antihypertensive and antisecretory activities with various structural modifications of the antihypertensive agent… 
Highly Cited
1965
Highly Cited
1965
STUDIES ON THE ACTIVE CENTER OF TRYPSIN. THE BINDING OF AMIDINES AND GUANIDINES AS MODELS OF THE SUBSTRATE SIDE CHAIN.