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Growth Differentiation Factor 15

Known as: Macrophage Inhibitory Cytokine 1, Differentiation Factor, Prostate, Prostate Differentiation Factor 
A growth differentiation factor that is secreted in response to cell stress and in response to MACROPHAGE ACTIVATION. In addition growth… 
National Institutes of Health

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Related topics

13 relations
C18orf8 geneGDF15 geneGDF15 wt AlleleIn Blood

Narrower (2)

GDF15 protein, humanGdf15 protein, mouse

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
The impact of GDF-15, a biomarker for metformin, on the risk of coronary artery disease, breast and colorectal cancer, and type 2 diabetes and metabolic traits: a Mendelian randomisation study
Aims/hypothesisGrowth differentiation factor 15 (GDF-15), a suggested biomarker for metformin use, may explain the potential… 
Review
2016
Review
2016
GDF 15 - A Novel Biomarker in the Offing for Heart Failure
Background: Several diagnostic and prognostic biomarkers are being explored in heart failure. GDF-15 belongs to the transforming… 
2015
2015
Risk scores and biomarkers for the prediction of 1-year outcome after transcatheter aortic valve replacement.
2014
2014
Growth Differentiation Factor-15 as Biomarker in Uterine Sarcomas
Objective The aim of this study was to investigate and validate circulating growth differentiation factor-15 (GDF-15) as a… 
2014
2014
Growth-Differentiation Factor-15 and Major Cardiac Events
Background:Growth-differentiation factor (GDF)-15 is a strong predictor of cardiovascular events in patients with ST-elevation… 
Highly Cited
2011
Highly Cited
2011
Growth Differentiation Factor-15 and Risk of Recurrent Events in Patients Stabilized After Acute Coronary Syndrome: Observations From PROVE IT-TIMI 22
Objective—To investigate growth differentiation factor (GDF)-15 at hospital discharge for assessment of the risk of death… 
2010
2010
Loss of GDF-15 abolishes Sulindac chemoprevention in the ApcMin/+ mouse model of intestinal cancer
BackgroundGrowth-differentiation factor (GDF)-15, a member of the TGF-beta superfamily, is potently induced in the intestine… 
Highly Cited
2010
Highly Cited
2010
Regulation of GDF-15, a distant TGF-β superfamily member, in a mouse model of cerebral ischemia
GDF-15 is a novel distant member of the TGF-β superfamily and is widely distributed in the brain and peripheral nervous system… 
2009
2009
Growth Differentiation Factor-15: a New Biomarker in Cardiovascular Disease
AbstractGrowth differentiation factor-(GDF-)15 is a stress-responsive cytokine that is emerging as a biomarker of cardiac and… 
Highly Cited
2009
Highly Cited
2009
Alterations of systemic and muscle iron metabolism in human subjects treated with low-dose recombinant erythropoietin.
The high iron demand associated with enhanced erythropoiesis during high-altitude hypoxia leads to skeletal muscle iron… 
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