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GDF15 gene

Known as: growth differentiation factor 15, BONE MORPHOGENETIC PROTEIN, PLACENTA, prostate differentiation factor 
This gene is involved in the regulation of tissue differentiation. It also plays a role in controlling the growth of granulocytes and macrophages.
National Institutes of Health

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Cell Differentiation processCell Proliferation Regulatory ProcessGDF15 protein, humanGrowth Differentiation Factor 15

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GDF15 wt Allele

Papers overview

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Review
2016
Review
2016
Long Non-coding RNAs in Urologic Malignancies: Functional Roles and Clinical Translation
Early diagnosis and surveillance for metastasis and recurrences are critical issues of urologic cancer. Deregulation of long non… 
2014
2014
Opposing Effects of PI3K/Akt and Smad-Dependent Signaling Pathways in NAG-1-Induced Glioblastoma Cell Apoptosis
Nonsteroidal anti-inflammatory drug (NSAID) activated gene-1 (NAG-1) is a divergent member of the transforming growth factor-beta… 
2014
2014
GDF15 regulates Kv2.1-mediated outward K+ current through the Akt/mTOR signalling pathway in rat cerebellar granule cells
GDF15 (growth/differentiation factor 15), a novel member of the TGFβ (transforming growth factor β) superfamily, plays critical… 
2012
2012
Pseudolaric Acid B Induces Caspase-Dependent and Caspase-Independent Apoptosis in U87 Glioblastoma Cells
Pseudolaric acid B (PLAB) is one of the major bioactive components of Pseudolarix kaempferi. It has been reported to exhibit… 
2012
2012
The H6D variant of NAG‐1/GDF15 inhibits prostate xenograft growth in vivo
Non‐steroidal anti‐inflammatory drug‐activated gene (NAG‐1), a divergent member of the transforming growth factor‐beta… 
2011
2011
Genetic markers to discriminate benign and malignant thyroid nodules with undetermined cytology in an area of borderline iodine deficiency
Fine needle aspiration (FNA) with cytologic evaluation is the most reliable tool for malignancy prediction in thyroid nodules… 
2009
2009
Reference change values and determinants of variability of NT-proANP and GDF15 in stable chronic heart failure
Biovariability, reference change values (RCV), and index of individuality (IOI) have not been previously described for NT-proANP… 
2008
2008
TAp63-dependent induction of growth differentiation factor 15 (GDF15) plays a critical role in the regulation of keratinocyte differentiation
Since p63-deficient mice display severe defects in formation of epidermis, p63 has been considered to be a multi-isoform p53… 
2008
2008
TFF3-based candidate gene discrimination of benign and malignant thyroid tumors in a region with borderline iodine deficiency.
BACKGROUND With the advent of microarray technology, increasing numbers of marker genes are proposed to distinguish benign and… 
2008
2008
Does the 3‐gene diagnostic assay accurately distinguish benign from malignant thyroid neoplasms?
A 3‐gene (PCSK2, PLAB, CCND2) assay has been reported to have high accuracy for distinguishing benign from malignant thyroid… 
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