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GDF15 protein, human

Known as: macrophage inhibitory cytokine-1 protein, human, NSAID-Regulated Gene 1 Protein, non-steroidal anti-inflammatory drug-activated gene-1 protein, human 
Growth/differentiation factor 15 (308 aa, ~34 kDa) is encoded by the human GDF15 gene. This protein plays a role in both tissue differentiation and… 
National Institutes of Health

Related topics

Related topics

13 relations
C18orf8 geneCell Differentiation processCell Proliferation Regulatory ProcessExtracellular Space

Broader (1)

Growth Differentiation Factor 15

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2017
Highly Cited
2017
Non-homeostatic body weight regulation through a brainstem-restricted receptor for GDF15
Under homeostatic conditions, animals use well-defined hypothalamic neural circuits to help maintain stable body weight, by… 
Highly Cited
2017
Highly Cited
2017
GFRAL is the receptor for GDF15 and is required for the anti-obesity effects of the ligand
Growth differentiation factor 15 (GDF15; also known as MIC-1) is a divergent member of the TGF-β superfamily and is associated… 
Review
2014
Review
2014
Neuregulin-ERBB Signaling in the Nervous System and Neuropsychiatric Diseases
Review
2014
Review
2014
Mechanisms regulating the development of oligodendrocytes and central nervous system myelin
Highly Cited
2010
Highly Cited
2010
Control of cortical GABA circuitry development by Nrg1 and ErbB4 signalling
Schizophrenia is a complex disorder that interferes with the function of several brain systems required for cognition and normal… 
Highly Cited
2007
Highly Cited
2007
Notch signaling is essential for ventricular chamber development.
Highly Cited
2002
Highly Cited
2002
Modulation of Anthracycline-Induced Myofibrillar Disarray in Rat Ventricular Myocytes by Neuregulin-1&bgr; and Anti-erbB2: Potential Mechanism for Trastuzumab-Induced Cardiotoxicity
Background—There is an increased incidence of heart failure in patients treated concurrently with anthracyclines and the… 
Highly Cited
2002
Highly Cited
2002
Snf1 Protein Kinase and the Repressors Nrg1 and Nrg2 Regulate FLO11, Haploid Invasive Growth, and Diploid Pseudohyphal Differentiation
ABSTRACT The Snf1 protein kinase of Saccharomyces cerevisiae is important for many cellular responses to glucose limitation… 
Highly Cited
2001
Highly Cited
2001
NRG1, a repressor of filamentous growth in C.albicans, is down‐regulated during filament induction
In response to a variety of external signals, the fungal pathogen Candida albicans undergoes a transition between ellipsoidal… 
Highly Cited
1997
Highly Cited
1997
Neuregulin-2, a new ligand of ErbB3/ErbB4-receptor tyrosine kinases
The neuregulins (NRGs) are a family of multipotent epidermal-growth-factor-like (EGF-like) factors that arise from splice… 
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