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Glypican

Known as: Glypicans, Glypicans [Chemical/Ingredient] 
A family of GLYCOSYLPHOSPHATIDYLINOSITOL-anchored, cell-surface heparan sulfate proteoglycans that may play a role in CELL GROWTH PROCESSES and CELL… 
National Institutes of Health

Related topics

Related topics

22 relations
GPC1 geneGPC2 geneIn BloodProcess of secretion

Narrower (9)

GPC3 protein, humanGPC3 protein, mouseGPC5 protein, humanGPC6 protein, human

Broader (2)

Heparitin SulfateProteoglycan

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
Comparative genetic screens in human cells reveal new regulatory mechanisms in WNT signaling
The comprehensive understanding of cellular signaling pathways remains a challenge due to multiple layers of regulation that may… 
2008
2008
Opposing roles for glypicans in Hedgehog signalling
Glypican members of the heparan sulphate proteoglycan family regulate several developmental signalling pathways, such as those… 
2007
2007
Effect of syndecan-1, syndecan-4, and glypican-1 on turkey muscle satellite cell proliferation, differentiation, and responsiveness to fibroblast growth factor 2.
The membrane-associated heparan sulfate proteoglycan families consisting of the syndecans and glypicans are low-affinity… 
2007
2007
The effect of glypican-1 glycosaminoglycan chains on turkey myogenic satellite cell proliferation, differentiation, and fibroblast growth factor 2 responsiveness.
The glypicans are a family of cell-surface heparan sulfate proteoglycans consisting of a core protein covalently attached with… 
Highly Cited
2006
Highly Cited
2006
Differential expression of membrane-associated heparan sulfate proteoglycans in the skeletal muscle of turkeys with different growth rates.
Heparan sulfate proteoglycans (HSPG) are key components of the cell membrane and extracellular matrix of skeletal muscle cells… 
Highly Cited
2005
Highly Cited
2005
Processing by Convertases Is Not Required for Glypican-3-induced Stimulation of Hepatocellular Carcinoma Growth*
Glypicans are a family of heparan sulfate proteoglycans that are bound to the cell surface by a lipid anchor. Six members of this… 
Highly Cited
2005
Highly Cited
2005
Gene expression profiling of a clonal isolate of oxaliplatin-resistant ovarian carcinoma cell line A2780/C10.
The efficacy of platinum drugs in the treatment of cancer is often restricted by the acquisition of tumor cell resistance… 
1998
1998
Evidence that glypican is a receptor mediating β‐amyloid neurotoxicity in PC12 cells
Docking of β‐amyloid fibrils to neuronal or glial cell membranes may be an early, necessary and intervenable step during the… 
1998
1998
Organization, 5'-flanking sequence and promoter activity of the rat GPC1 gene.
1996
1996
Expression of avian glypican is developmentally regulated
An avian cDNA homologue of human and rat glypicans has been cloned from a stage 17 chicken heart cDNA library and used to analyze… 
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