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Glypican

Known as: Glypicans, Glypicans [Chemical/Ingredient] 
A family of GLYCOSYLPHOSPHATIDYLINOSITOL-anchored, cell-surface heparan sulfate proteoglycans that may play a role in CELL GROWTH PROCESSES and CELL… 
National Institutes of Health

Related topics

Related topics

22 relations
GPC1 geneGPC2 geneIn BloodProcess of secretion

Narrower (9)

GPC3 protein, humanGPC3 protein, mouseGPC5 protein, humanGPC6 protein, human

Broader (2)

Heparitin SulfateProteoglycan

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2015
Highly Cited
2015
Heparanase activates the syndecan-syntenin-ALIX exosome pathway
Exosomes are secreted vesicles of endosomal origin involved in signaling processes. We recently showed that the syndecan heparan… 
Review
2009
Review
2009
Proteoglycan signaling co-receptors: roles in cell adhesion, migration and invasion.
Highly Cited
2005
Highly Cited
2005
Drosophila glypicans Dally and Dally-like shape the extracellular Wingless morphogen gradient in the wing disc
Drosophila Wingless (Wg) is the founding member of the Wnt family of secreted proteins. During the wing development, Wg acts as a… 
Highly Cited
2004
Highly Cited
2004
Drosophila glypicans control the cell-to-cell movement of Hedgehog by a dynamin-independent process
The signalling molecule Hedgehog (Hh) functions as a morphogen to pattern a field of cells in animal development. Previous… 
Review
2004
Review
2004
Novel aspects of glypican glycobiology
Mutations in glypican genes cause dysmorphic and overgrowth syndromes in men and mice, abnormal development in flies and worms… 
Highly Cited
2003
Highly Cited
2003
The glypican Dally-like is required for Hedgehog signalling in the embryonic epidermis of Drosophila
The Drosophila genes dally and dally-like encode glypicans, which are heparan sulphate proteoglycans anchored to the cell… 
Review
2001
Review
2001
Glypicans in growth control and cancer.
The name glypican has been assigned to a family of heparan sulfate (HS) proteoglycans that are linked to the cell membrane by a… 
Review
2000
Review
2000
Heparan sulfate proteoglycans on the cell surface: versatile coordinators of cellular functions.
Review
2000
Review
2000
Proteoglycans in the developing brain: new conceptual insights for old proteins.
Proteoglycans are a heterogeneous class of proteins bearing sulfated glycosaminoglycans. Some of the proteoglycans have distinct… 
Highly Cited
1999
Highly Cited
1999
Glypican-1 Is a VEGF165 Binding Proteoglycan That Acts as an Extracellular Chaperone for VEGF165 *
Glypican-1 is a member of a family of glycosylphosphatidylinositol anchored cell surface heparan sulfate proteoglycans implicated… 
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